AIMC Topic: Severity of Illness Index

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Incidence of severe renal dysfunction among individuals taking warfarin and implications for non-vitamin K oral anticoagulants.

American heart journal
BACKGROUND: The purpose of this study is to assess incidence and risk factors for severe renal dysfunction in patients requiring oral anticoagulation to help guide initial drug choice and provide a rational basis for interval monitoring of renal func...

Predicting symptom severity in autism spectrum disorder based on cortical thickness measures in agglomerative data.

NeuroImage
Machine learning approaches have been widely used for the identification of neuropathology from neuroimaging data. However, these approaches require large samples and suffer from the challenges associated with multi-site, multi-protocol data. We prop...

Machine learning approaches to personalize early prediction of asthma exacerbations.

Annals of the New York Academy of Sciences
Patient telemonitoring results in an aggregation of significant amounts of information about patient disease trajectory. However, the potential use of this information for early prediction of exacerbations in adult asthma patients has not been system...

Accuracy of automated classification of major depressive disorder as a function of symptom severity.

NeuroImage. Clinical
BACKGROUND: Growing evidence documents the potential of machine learning for developing brain based diagnostic methods for major depressive disorder (MDD). As symptom severity may influence brain activity, we investigated whether the severity of MDD ...

Longitudinal clinical score prediction in Alzheimer's disease with soft-split sparse regression based random forest.

Neurobiology of aging
Alzheimer's disease (AD) is an irreversible neurodegenerative disease and affects a large population in the world. Cognitive scores at multiple time points can be reliably used to evaluate the progression of the disease clinically. In recent studies,...

Robotic Transcatheter Mitral Valve Replacement Using the Sapien XT in the Setting of Severe Mitral Annular Calcification.

Journal of cardiac surgery
We describe the use of the Sapien XT, placed in the mitral position using a totally endoscopic robotic approach in a 76-year-old man with extensive circumferential mitral calcifications and severe stenosis. The patient was at high risk for traditiona...

Automatic assessment of mitral regurgitation severity based on extensive textural features on 2D echocardiography videos.

Computers in biology and medicine
Heart disease is the major cause of death as well as a leading cause of disability in the developed countries. Mitral Regurgitation (MR) is a common heart disease which does not cause symptoms until its end stage. Therefore, early diagnosis of the di...