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Sodium

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Sodium adduct formation with graph-based machine learning can aid structural elucidation in non-targeted LC/ESI/HRMS.

Analytica chimica acta
Non-targeted screening with LC/ESI/HRMS aims to identify the structure of the detected compounds using their retention time, exact mass, and fragmentation pattern. Challenges remain in differentiating between isomeric compounds. One untapped possibil...

The Role of GDF-15 in Heart Failure Patients With Chronic Kidney Disease.

The Canadian journal of cardiology
BACKGROUND: Growth differentiation factor-15 (GDF-15) is a stress-inducible cytokine and member of the transforming growth factor-β cytokine superfamily that refines prognostic assessment in subgroups of patients with heart failure (HF). We evaluated...

A statistically rigorous deep neural network approach to predict mortality in trauma patients admitted to the intensive care unit.

The journal of trauma and acute care surgery
BACKGROUND: Trauma patients admitted to critical care are at high risk of mortality because of their injuries. Our aim was to develop a machine learning-based model to predict mortality using Fahad-Liaqat-Ahmad Intensive Machine (FLAIM) framework. We...

Na MRI in ischemic stroke: Acquisition time reduction using postprocessing with convolutional neural networks.

NMR in biomedicine
Quantitative Na magnetic resonance imaging (MRI) provides tissue sodium concentration (TSC), which is connected to cell viability and vitality. Long acquisition times are one of the most challenging aspects for its clinical establishment. K-space un...

Rapid prototyping of ion-selective electrodes using a low-cost 3D printed internet-of-things (IoT) controlled robot.

Talanta
We report automated fabrication of solid-contact sodium-selective (Na-ISEs) and potassium-selective electrodes (K-ISEs) using a 3D printed liquid handling robot controlled with Internet of Things (IoT) technology. The printing system is affordable an...

Deep learning and the future of the Model for End-Stage Liver Disease-sodium score.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Multi-Branch-CNN: Classification of ion channel interacting peptides using multi-branch convolutional neural network.

Computers in biology and medicine
Ligand peptides that have high affinity for ion channels are critical for regulating ion flux across the plasma membrane. These peptides are now being considered as potential drug candidates for many diseases, such as cardiovascular disease and cance...