Arteriosclerosis, thrombosis, and vascular biology
Jan 2, 2025
Preeclampsia is a multisystem hypertensive disorder that manifests itself after 20 weeks of pregnancy, along with proteinuria. The pathophysiology of preeclampsia is incompletely understood. Artificial intelligence, especially machine learning with i...
Arteriosclerosis, thrombosis, and vascular biology
May 23, 2024
BACKGROUND: Analysis of vascular networks is an essential step to unravel the mechanisms regulating the physiological and pathological organization of blood vessels. So far, most of the analyses are performed using 2-dimensional projections of 3-dime...
Arteriosclerosis, thrombosis, and vascular biology
Jun 16, 2022
BACKGROUND: Coronary calcification associates closely with cardiovascular risk, but its progress is accelerated in response to some interventions widely used to reduce risk. This paradox suggests that qualitative, not just quantitative, changes in ca...
Arteriosclerosis, thrombosis, and vascular biology
Aug 12, 2021
Objective: Manual plaque segmentation in microscopy images is a time-consuming process in atherosclerosis research and potentially subject to unacceptable user-to-user variability and observer bias. We address this by releasing Vesseg a tool that inc...
Arteriosclerosis, thrombosis, and vascular biology
Dec 24, 2020
OBJECTIVE: Our aim was to characterize distinctive clinical antiphospholipid syndrome phenotypes and identify novel microRNA (miRNA)-mRNA-intracellular signaling regulatory networks in monocytes linked to cardiovascular disease. Approach and Results:...
Arteriosclerosis, thrombosis, and vascular biology
Mar 10, 2016
OBJECTIVE: Recent genome-wide association studies of coronary artery disease (CAD) have revealed 58 genome-wide significant and 148 suggestive genetic loci. However, the molecular mechanisms through which they contribute to CAD and the clinical impli...