AIMC Topic: Aged

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Deep learning detection of retinal detachment: Optical coherence tomography staging and estimation of duration of macular detachment.

PloS one
OBJECTIVE: To test the applicability of deep learning models for detecting and staging rhegmatogenous retinal detachment (RRD) based on morphological features using two- and three-dimensional optical coherence tomography (OCT) scans.

Association between hemoglobin glycation index and 28-day all-cause mortality in acute myocardial infarction patients: Analysis of the MIMIC-IV database.

PloS one
Acute myocardial infarction (AMI) substantially fuels the worldwide escalation in both morbidity and mortality. The hemoglobin glycation index (HGI) is linked to a range of undesirable outcomes, but its relationship with short-term outcomes in AMI pa...

Fibro predict a machine learning risk score for advanced liver fibrosis in the general population using Israeli electronic health records.

Scientific reports
Liver diseases, notably cirrhosis, pose a substantial global health challenge, resulting in millions of annual deaths. Existing diagnostic methods primarily target high-risk groups, leaving a significant portion of patients undiagnosed. This study ai...

Pulmonary Embolism Survival Prediction Using Multimodal Learning Based on Computed Tomography Angiography and Clinical Data.

Journal of thoracic imaging
PURPOSE: Pulmonary embolism (PE) is a significant cause of mortality in the United States. The objective of this study is to implement deep learning (DL) models using computed tomography pulmonary angiography (CTPA), clinical data, and PE Severity In...

Lipid metabolites as biomarkers and therapeutic targets in oral squamous cell carcinoma.

BMC oral health
This study explores the association of lipid metabolism disruption and Oral Squamous Cell Carcinoma (OSCC). We aim to identify specific lipid biomarkers and therapeutic targets for OSCC. We included 78 OSCC patients and 80 healthy controls, and appli...

Divergent biological pathways distinguish community-acquired pneumonia from COVID-19 despite similar plasma cytokine profiles.

Respiratory research
BACKGROUND: Pulmonary infections, ranging from mild respiratory issues to severe multiorgan failure, pose a major global health threat. The immune response in community-acquired pneumonia (CAP) and COVID-19 influences disease severity and outcomes, b...

Noncontrast CT-based deep learning for predicting intracerebral hemorrhage expansion incorporating growth of intraventricular hemorrhage.

Scientific reports
Intracerebral hemorrhage (ICH) is a severe form of stroke with high mortality and disability, where early hematoma expansion (HE) critically influences prognosis. Previous studies suggest that revised hematoma expansion (rHE), defined to include intr...

Factors associated with admission to elderly medical-welfare facilities in South Korea: a cross-sectional machine-learning study.

BMJ open
OBJECTIVES: To identify the key factors associated with admission to elderly medical-welfare facilities in South Korea and to evaluate their relative importance using machine learning techniques, providing an evidence base for policy in a rapidly age...

External validation of deep learning-derived 18F-FDG PET/CT delta biomarkers for loco-regional control in head and neck cancer.

Acta oncologica (Stockholm, Sweden)
BACKGROUND AND PURPOSE: Delta biomarkers that reflect changes in tumour burden over time can support personalised follow-up in head and neck cancer. However, their clinical use can be limited by the need for manual image segmentation. This study exte...

Fusion model integrating multi-sequence MRI radiomics and habitat imaging for predicting pathological complete response in breast cancer treated with neoadjuvant therapy.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: This study aimed to develop a predictive model integrating multi-sequence MRI radiomics, deep learning features, and habitat imaging to forecast pathological complete response (pCR) in breast cancer patients undergoing neoadjuvant therapy...