OBJECTIVES: Accurate and noninvasive detection of p53 status in isocitrate dehydrogenase mutant (IDH-mt) glioma is clinically meaningful for molecular stratification of glioma, yet it remains challenging. We aimed to investigate the diagnostic effica...
BACKGROUND: With the widespread adoption of low-dose CT screening, the detection of pulmonary ground-glass nodules (GGNs) has risen markedly, presenting diagnostic challenges in distinguishing preinvasive lesions from invasive adenocarcinomas (IAC). ...
BACKGROUND: Predicting the prognosis of patients with acute cerebral infarction (ACI) is crucial for clinical decision-making and personalized treatment. However, existing models often lack the comprehensive integration of clinical and biological ind...
OBJECTIVE: To evaluate the effect of deep learning (DL)-based artificial intelligence (AI) software on the diagnostic performance of radiologists with different experience levels in detecting nigrosome 1 (N1) abnormalities on susceptibility map-weigh...
Journal of cellular and molecular medicine
Aug 1, 2025
The immunoregulatory functions and clinical implications of APOE+ macrophages within the tumour microenvironment of lung adenocarcinoma remain incompletely defined. In this study, single-cell transcriptome analysis revealed distinct subsets of APOE+ ...
Neuropathology : official journal of the Japanese Society of Neuropathology
Aug 1, 2025
This study aimed to evaluate the performance of ChatGPT-4.0 as a diagnostic support tool for pathologists in identifying different types of gliomas based on histopathological data and to compare its performance with that of another artificial intelli...
BACKGROUND: Glucagon-like Peptide-1 Receptor Agonists (GLP1RA) may reduce asthma exacerbation (AE) risk, but it is unclear which populations benefit most. Recent pharmacoepidemiologic studies have employed iterative causal forest (iCF), a machine lea...
Journal of cachexia, sarcopenia and muscle
Aug 1, 2025
BACKGROUND: The diagnosis of malnutrition has evolved with the GLIM recommendations, which advocate for integrating phenotypic criteria, including muscle mass measurement. The GLIM framework specifically suggests using skeletal muscle index (SMI) ass...
Journal of applied clinical medical physics
Aug 1, 2025
BACKGROUND: Current approaches to lung parcellation utilize established fissures between lobes to provide estimates of lobar volume. However, deep learning segment parcellation provides the ability to better assess regional heterogeneity in ventilati...
Predicting brain age from T1-weighted MRI is a promising marker for understanding brain aging and its associated conditions. While deep learning models have shown success in reducing the mean absolute error (MAE) of predicted brain age, concerns abou...
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