AIMC Topic: Aged

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Machine learning for predicting all-cause mortality of metabolic dysfunction-associated fatty liver disease: a longitudinal study based on NHANES.

BMC gastroenterology
BACKGROUND: The mortality burden of metabolic dysfunction-associated fatty liver disease (MAFLD) is rising, making it crucial to predict mortality and identify the factors influencing it. While advanced machine learning algorithms are gaining recogni...

Machine learning for grading prediction and survival analysis in high grade glioma.

Scientific reports
We developed and validated a magnetic resonance imaging (MRI)-based radiomics model for the classification of high-grade glioma (HGG) and determined the optimal machine learning (ML) approach. This retrospective analysis included 184 patients (59 gra...

Evaluation of a Machine Learning Model Based on Laboratory Parameters for the Prediction of Influenza A and B in Chongqing, China: Multicenter Model Development and Validation Study.

Journal of medical Internet research
BACKGROUND: Influenza viruses are major pathogens responsible for acute respiratory infections in humans, which present with symptoms such as fever, cough, sore throat, muscle pain, and fatigue. While molecular diagnostics remain the gold standard, t...

Patients' Perceptions of Artificial Intelligence Acceptance, Challenges, and Use in Medical Care: Qualitative Study.

Journal of medical Internet research
BACKGROUND: Artificial intelligence (AI) is increasingly used in medical care, particularly in the areas of image recognition and processing. While its practical use in other areas is still limited, an understanding of patients' needs is essential fo...

Extracting Multifaceted Characteristics of Patients With Chronic Disease Comorbidity: Framework Development Using Large Language Models.

JMIR medical informatics
BACKGROUND: Research on chronic multimorbidity has increasingly become a focal point with the aging of the population. Many studies in this area require detailed patient characteristic information. However, the current methods for extracting such inf...

Deep Learning-Based Chronic Obstructive Pulmonary Disease Exacerbation Prediction Using Flow-Volume and Volume-Time Curve Imaging: Retrospective Cohort Study.

Journal of medical Internet research
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common and progressive respiratory condition characterized by persistent airflow limitation and symptoms such as dyspnea, cough, and sputum production. Acute exacerbations (AE) of COPD (AE...

A Deep Learning-Enabled Workflow to Estimate Real-World Progression-Free Survival in Patients With Metastatic Breast Cancer: Study Using Deidentified Electronic Health Records.

JMIR cancer
BACKGROUND: Progression-free survival (PFS) is a crucial endpoint in cancer drug research. Clinician-confirmed cancer progression, namely real-world PFS (rwPFS) in unstructured text (ie, clinical notes), serves as a reasonable surrogate for real-worl...

Deep learning MRI-based radiomic models for predicting recurrence in locally advanced nasopharyngeal carcinoma after neoadjuvant chemoradiotherapy: a multi-center study.

Clinical & experimental metastasis
Local recurrence and distant metastasis were a common manifestation of locoregionally advanced nasopharyngeal carcinoma (LA-NPC) after neoadjuvant chemoradiotherapy (NACT). To validate the clinical value of MRI radiomic models based on deep learning ...

Boi-Ogi-To, a Traditional Japanese Kampo Medicine, Promotes Cellular Excretion of Chloride and Water by Activating Volume-Sensitive Outwardly Rectifying Anion Channels.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
The Japanese Kampo medicine Boi-ogi-to (BOT) is known as an effective therapeutic agent for edema and nephrosis by promoting the excretion of excess body fluids. Despite its empirical effectiveness, scientific evidence supporting its effectiveness re...

Clinical Implications of The Cancer Genome Atlas Molecular Classification System in Esophagogastric Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: The Cancer Genome Atlas (TCGA) project defined four distinct molecular subtypes of esophagogastric adenocarcinoma: microsatellite instable (MSI), Epstein-Barr virus (EBV)-associated, genomically stable (GS), and chromosomally instable (CIN)....