AIMC Topic: Animals

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Enhanced antitumor efficacy of doxorubicin-encapsulated halloysite nanotubes.

International journal of nanomedicine
To improve the antitumor efficacy of doxorubicin (DOX) and provide novel clinical treatment of gastric cancer, halloysite nanotubes (HNTs) loaded with DOX were encapsulated by soybean phospholipid (LIP) and the formed HNTs/DOX/LIP was systematically ...

Milking machine and udder health management factors associated with bulk milk somatic cell count in Uruguayan herds.

Preventive veterinary medicine
This paper describes the findings of static milking machine tests and milking observations on Uruguayan dairy farms. The aim of this study was to investigate the association between both milking machine performance and udder health management factors...

Nitric oxide-releasing injectable hydrogels with high antibacterial activity through in situ formation of peroxynitrite.

Acta biomaterialia
UNLABELLED: Nitric oxide (NO) is an endogenous molecule with many critical biological functions that depend on its concentration. At high levels, NO provides broad-spectrum antibacterial effects through both its pathogen inhibition and killing abilit...

Inhibitory activity of linarin on osteoclastogenesis through receptor activator of nuclear factor κB ligand-induced NF-κB pathway.

Biochemical and biophysical research communications
Linarin, a natural flavonoid glycoside widely found in plants, has been reported to possess anti-inflammation, neuroprotection and osteogenic properties. However, its impact on osteoclast remains unclear. In the present study, the effects of linarin ...

Effect of dacarbazine on CD44 in live melanoma cells as measured by atomic force microscopy-based nanoscopy.

International journal of nanomedicine
CD44 ligand-receptor interactions are known to be involved in regulating cell migration and tumor cell metastasis. High expression levels of CD44 correlate with a poor prognosis of melanoma patients. In order to understand not only the mechanistic ba...

Angiotensin Converting Enzyme Inhibitory and Antioxidant Activities of Enzymatic Hydrolysates of Korean Native Cattle (Hanwoo) Myofibrillar Protein.

BioMed research international
The purpose of this study was to determine the angiotensin converting enzyme (ACE) inhibitory and antioxidant activities of myofibrillar protein hydrolysates (HMPHs) of different molecular weights (<3 and <10 kDa) derived from Korean native cattle (H...

Robustness in living organisms is homeostasis.

Seminars in immunology
In order to survive and reproduce, living organisms must be robust, tolerate injuries and undergo repair. Robustness in living organisms compares to robustness in human inventions, such as buildings and machines, which have to withstand occasional da...

Toltrazuril mixed nanomicelle delivery system based on sodium deoxycholate-Brij C20 polyethylene ether-triton x100: Characterization, solubility, and bioavailability study.

Colloids and surfaces. B, Biointerfaces
Toltrazuril (Tol) is a broad-spectrum anticoccidiosis drug that is widely used in the prevention and treatment of coccidiosis infection in poultry and mammals. However, the drug has poor aqueous solubility (25 °C, 0.41 μg/mL), and its dose escalation...

Somatic cell count and type of intramammary infection impacts fertility from in vitro produced embryo transfer.

Theriogenology
The objective of this study was to assess the impact of mastitis-causing bacteria and somatic cell count (SCC) on pregnancy per embryo transfer (P/ET) in Holstein-Gir crossbred (Girolando) lactating dairy cows. Cows (n = 1397) were subjected to a tim...