AIMC Topic: Anti-Inflammatory Agents
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BIOLOGICAL AND PHYTOCHEMICAL INVESTIGATIONS OF EXTRACTS FROM POIR (FABACEAE) ROOT BARKS.
African journal of traditional, complementary, and alternative medicines : AJTCAM
Nov 23, 2016
BACKGROUND: Poir. belonging to Fabacae familly is used as medicinal plant in Burkina Faso's folk medicine. Roots of are used to treat ulcer, stomach ache and inflammatory diseases. The objective of the present study was to carry out phytochemical c...
A Multicenter Study of Early Anti-inflammatory Treatment in Patients With Acute Anterior Cruciate Ligament Tear.
The American journal of sports medicine
Oct 7, 2016
BACKGROUND: It is increasingly recognized that biochemical abnormalities of the joint precede radiographic abnormalities of posttraumatic osteoarthritis (PTOA) by as much as decades. A growing body of evidence strongly suggests that the progression f...
NITRIC OXIDE INHIBITORY ACTIVITY OF (LOGANIACEAE) LEAF EXTRACTS AND FRACTIONS.
African journal of traditional, complementary, and alternative medicines : AJTCAM
Sep 29, 2016
BACKGROUND: The study was aimed at determining the anti-inflammatory activity of fractions and extracts obtained from leaves on a mediator of inflammation nitric oxide (NO).
Improving Sexual Function Recovery Following RARP: Impact of Surgeon Technique Versus the Role of Anti-Inflammatory Agents? Editorial Comment for Patel et al.
Journal of endourology
Jun 17, 2016
Hericium erinaceus Inhibits TNF-α-Induced Angiogenesis and ROS Generation through Suppression of MMP-9/NF-κB Signaling and Activation of Nrf2-Mediated Antioxidant Genes in Human EA.hy926 Endothelial Cells.
Oxidative medicine and cellular longevity
Dec 28, 2015
Hericium erinaceus (HE) is an edible mushroom that has been shown to exhibit anticancer and anti-inflammatory activities. We investigated the antiangiogenic and antioxidant potentials of ethanol extracts of HE in human endothelial (EA.hy926) cells up...
Basidiomycota
Endothelial Cells
NF-E2-Related Factor 2
Angiogenesis Inducing Agents
Intercellular Adhesion Molecule-1
Neovascularization, Pathologic
Heme Oxygenase-1
Glutathione
NF-kappa B
Anti-Inflammatory Agents
Matrix Metalloproteinase 9
Humans
Tumor Necrosis Factor-alpha
Antioxidants
Inflammation
Signal Transduction
Angiogenesis Inhibitors
Reactive Oxygen Species
Steroids Improve Hemodynamics in Infants With Adrenal Insufficiency After Cardiac Surgery.
Journal of cardiothoracic and vascular anesthesia
Nov 27, 2015
OBJECTIVE: To investigate whether steroid replacement therapy improved hemodynamics in infants after surgery for congenital heart disease only when they develop adrenal insufficiency. The authors retrospectively investigated adrenal function and eval...
Comparative evaluation of different cultivars of Flos Chrysanthemi by an anti-inflammatory-based NF-κB reporter gene assay coupled to UPLC-Q/TOF MS with PCA and ANN.
Journal of ethnopharmacology
Aug 29, 2015
ETHNOPHARMACOLOGICAL RELEVANCE: Flos Chrysanthemi (FC), a commonly used traditional Chinese medicine, has five major cultivars ("Boju", "Chuju", "Gongju", "Hangbaiju" and "Huaiju") from different sources. However, the active constituents of these cul...
Prediction of Anti-inflammatory Plants and Discovery of Their Biomarkers by Machine Learning Algorithms and Metabolomic Studies.
Planta medica
Jan 23, 2015
Nonsteroidal anti-inflammatory drugs are the most used anti-inflammatory medicines in the world. Side effects still occur, however, and some inflammatory pathologies lack efficient treatment. Cyclooxygenase and lipoxygenase pathways are of utmost imp...
Exploration of Active Substances and Its Potential Mechanism of Gancao Fuzi Decoction on Inflammatory Based on Metabolomics and Network Pharmacology.
Rapid communications in mass spectrometry : RCM
May 30, 2025
Gancao Fuzi decoction (GCFZT) is a traditional Chinese formula, which has been commonly used in clinical practice to treat inflammatory diseases. However, the active substance of GCFZT in the treatment of inflammation is not fully clarified. In this ...
AI-Driven Design and Development of Nontoxic DYRK1A Inhibitors.
Journal of medicinal chemistry
May 22, 2025
Dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) is implicated in several human diseases, including DYRK1A syndrome, cancer, and neurodegenerative disorders such as Alzheimer's disease, making it a relevant therapeutic target. I...
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