AIMC Topic: Benzothiazoles
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A deep learning model for generating [F]FDG PET Images from early-phase [F]Florbetapir and [F]Flutemetamol PET images.
European journal of nuclear medicine and molecular imaging
Jun 11, 2024
INTRODUCTION: Amyloid-β (Aβ) plaques is a significant hallmark of Alzheimer's disease (AD), detectable via amyloid-PET imaging. The Fluorine-18-Fluorodeoxyglucose ([F]FDG) PET scan tracks cerebral glucose metabolism, correlated with synaptic dysfunct...
Optimization of catalytic wet air oxidation process in microchannel reactor for TBBS wastewater treatment.
Environmental technology
Nov 24, 2023
Catalytic wet air oxidation (CWAO) process is employed for the treatment of N-tert-butyl-2-benzothiazolesulfenamide (TBBS) wastewater in a microchannel reactor that enables continuous operation of the reaction and allows for thorough mixing of oxygen...
Deep learning-guided joint attenuation and scatter correction in multitracer neuroimaging studies.
Human brain mapping
May 21, 2020
PET attenuation correction (AC) on systems lacking CT/transmission scanning, such as dedicated brain PET scanners and hybrid PET/MRI, is challenging. Direct AC in image-space, wherein PET images corrected for attenuation and scatter are synthesized f...
A mitochondria-targeting nitroreductase fluorescent probe with large Stokes shift and long-wavelength emission for imaging hypoxic status in tumor cells.
Analytica chimica acta
Dec 24, 2019
Development of a mitochondria-targeting fluorescent probe with large Stokes shift and long-wavelength emission was benefit for accurate detection of hypoxic status, which was known as a major factor of the tumor physiology and influence important pat...
Predicting drug response of tumors from integrated genomic profiles by deep neural networks.
BMC medical genomics
Jan 31, 2019
BACKGROUND: The study of high-throughput genomic profiles from a pharmacogenomics viewpoint has provided unprecedented insights into the oncogenic features modulating drug response. A recent study screened for the response of a thousand human cancer ...
Extraction, identification and structure-activity relationship of antioxidant peptides from sesame (Sesamum indicum L.) protein hydrolysate.
Food research international (Ottawa, Ont.)
Sep 4, 2018
To elucidate the sequence, origin and structure-activity relationship of antioxidant peptides from sesame protein, sesame protein was hydrolysed by a dual-enzyme system comprised alcalase and trypsin, then this hydrolysate was fractionated by ultrafi...
Adaptive template generation for amyloid PET using a deep learning approach.
Human brain mapping
May 11, 2018
Accurate spatial normalization (SN) of amyloid positron emission tomography (PET) images for Alzheimer's disease assessment without coregistered anatomical magnetic resonance imaging (MRI) of the same individual is technically challenging. In this st...
Label-free detection of histone based on cationic conjugated polymer-mediated fluorescence resonance energy transfer.
Talanta
Dec 5, 2017
A simple and homogeneous histone assay is developed based on histone-induced DNA compressing coupled with cationic conjugated polymer (CCP)-mediated fluorescence resonance energy transfer (FRET). In this strategy, the CCP serves as the FRET donor and...
Integrating DNA structure switch with branched hairpins for the detection of uracil-DNA glycosylase activity and inhibitor screening.
Talanta
Nov 22, 2017
The detection of uracil-DNA glycosylase (UDG) activity is pivotal for its biochemical studies and the development of drugs for UDG-related diseases. Here, we explored an integrated DNA structure switch for high sensitive detection of UDG activity. Th...
Systematic evaluation of bioactive components and antioxidant capacity of some new and common bayberry cultivars using an in vitro gastrointestinal digestion method.
Food research international (Ottawa, Ont.)
Oct 31, 2017
This study was aimed to investigate the impact of in vitro gastrointestinal digestion on some common and new bayberry cultivars. The contents of total phenolics (246-669mg gallic acid equivalents/kg FW (fresh weight)), flavonoids (116-689mg quercetin...
Myrica
Benzothiazoles
Sulfonic Acids
Chlorides
Gastric Acid
Intestinal Secretions
Chromatography, High Pressure Liquid
Reactive Oxygen Species
Fruit
Phenols
Ferric Compounds
Caco-2 Cells
Digestion
Principal Component Analysis
Humans
Oxidation-Reduction
Oxidative Stress
Antioxidants
Mass Spectrometry
Dose-Response Relationship, Drug
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