AIMC Topic: Biomarkers

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Liver tissue segmentation in multiphase CT scans using cascaded convolutional neural networks.

International journal of computer assisted radiology and surgery
PURPOSE: We address the automatic segmentation of healthy and cancerous liver tissues (parenchyma, active and necrotic parts of hepatocellular carcinoma (HCC) tumor) on multiphase CT images using a deep learning approach.

An ensemble learning method for asthma control level detection with leveraging medical knowledge-based classifier and supervised learning.

Journal of medical systems
Approximately 300 million people are afflicted with asthma around the world, with the estimated death rate of 250,000 cases, indicating the significance of this disease. If not treated, it can turn into a serious public health problem. The best metho...

A machine learning approach to knee osteoarthritis phenotyping: data from the FNIH Biomarkers Consortium.

Osteoarthritis and cartilage
OBJECTIVE: Knee osteoarthritis (KOA) is a heterogeneous condition representing a variety of potentially distinct phenotypes. The purpose of this study was to apply innovative machine learning approaches to KOA phenotyping in order to define progressi...

Multiloss Function Based Deep Convolutional Neural Network for Segmentation of Retinal Vasculature into Arterioles and Venules.

BioMed research international
The arterioles and venules (AV) classification of retinal vasculature is considered as the first step in the development of an automated system for analysing the vasculature biomarker association with disease prognosis. Most of the existing AV classi...

Feature-weighted survival learning machine for COPD failure prediction.

Artificial intelligence in medicine
Chronic obstructive pulmonary disease (COPD) yields a high rate of failures such as hospital readmission and death in the United States, Canada and worldwide. COPD failure imposes a significant social and economic burden on society, and predicting su...

Non-invasive assessment of NAFLD as systemic disease-A machine learning perspective.

PloS one
BACKGROUND & AIMS: Current non-invasive scores for the assessment of severity of non-alcoholic fatty liver disease (NAFLD) and identification of patients with non-alcoholic steatohepatitis (NASH) have insufficient performance to be included in clinic...

RNA sequencing and swarm intelligence-enhanced classification algorithm development for blood-based disease diagnostics using spliced blood platelet RNA.

Nature protocols
Blood-based diagnostics tests, using individual or panels of biomarkers, may revolutionize disease diagnostics and enable minimally invasive therapy monitoring. However, selection of the most relevant biomarkers from liquid biosources remains an imme...

Artificial intelligence based discovery of the association between depression and chronic fatigue syndrome.

Journal of affective disorders
BACKGROUND: Both of the modern medicine and the traditional Chinese medicine classify depressive disorder (DD) and chronic fatigue syndrome (CFS) to one type of disease. Unveiling the association between depressive and the fatigue diseases provides a...

Predictive markers for Parkinson's disease using deep neural nets on neuromelanin sensitive MRI.

NeuroImage. Clinical
Neuromelanin sensitive magnetic resonance imaging (NMS-MRI) has been crucial in identifying abnormalities in the substantia nigra pars compacta (SNc) in Parkinson's disease (PD) as PD is characterized by loss of dopaminergic neurons in the SNc. Curre...