Postmenopausal osteoporosis (PMOP) increases the risk of periodontitis (PD), yet the shared mechanisms remain unclear. Rho-signal transduction genes may play a role due to their involvement in bone remodeling. This study aimed to explore Rho-related ...
BACKGROUND: Nonspecific orbital inflammation (NSOI), also known as idiopathic orbital inflammation, comprises a heterogeneous group of immune-mediated disorders affecting orbital tissues, unified by the absence of a defined etiology. Lactotransferrin...
BACKGROUND: Niacin Skin-Flushing Response (NSR) has emerged as a promising objective biomarker for the precise diagnosis of mental disorders. However, its diagnostic potential has been constrained by the limitations of traditional statistical approac...
BACKGROUND: Sphingolipid metabolism (SM) is linked to acute myocardial infarction (AMI), but its role remains unclear. This study explored SM-related genes (SMRGs) in AMI to support clinical diagnosis.
Exhaled gas detection offers a safe, convenient, and non-invasive clinical diagnostic method for preventing the progression of diabetes to complications. In this study, gas chromatography-mass spectrometry (GC-MS) analysis and statistical methods wer...
Chronic spontaneous urticaria is a common skin disorder with variable treatment responses. Second-generation H1-antihistamines are the first-line treatment for chronic spontaneous urticaria, yet many patients fail to respond to licensed doses. Predic...
Alzheimer's disease (AD) biomarkers (Aβ42 or Tau 181) have high diagnostic performance. However, when they are altered, it indicates that irreversible pathology has developed in the brain. Therefore, there is a lack of early prediction or monitoring ...
Metabolic dysfunction-associated steatotic liver disease (MASLD) in children with obesity correlates with metabolic dysfunction, yet interactions between anthropometrics, liver enzymes, and risk of MASLD remain unclear. This study included 219 childr...
BACKGROUND: Vascular depression (VaDep) is a prevalent affective disorder in older adults that significantly impacts functional status and quality of life. Early identification and intervention are crucial but largely insufficient in clinical practic...
Atrial fibrillation (AF) increases the risk of adverse cardiovascular events, yet the underlying biological mechanisms remain unclear. We evaluate a panel of 12 circulating biomarkers representing diverse pathophysiological pathways in 3817 AF patien...
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