AIMC Topic: Brachytherapy

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Focal MRI-Guided Salvage High-Dose-Rate Brachytherapy in Patients With Radiorecurrent Prostate Cancer.

Technology in cancer research & treatment Dec 5, 2017
INTRODUCTION: Whole-gland salvage treatment of radiorecurrent prostate cancer has a high rate of severe toxicity. The standard of care in case of a biochemical recurrence is androgen deprivation treatment, which is associated with morbidity and negat...
Salvage Therapy Brachytherapy Middle Aged Radiotherapy Dosage Radiation Injuries Prostatic Neoplasms Antigens, Surface Prostate Gallium Radioisotopes Humans Neoplasm Recurrence, Local Glutamate Carboxypeptidase II Aged Aged, 80 and over Male
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Deep convolutional neural network with transfer learning for rectum toxicity prediction in cervical cancer radiotherapy: a feasibility study.

Physics in medicine and biology Oct 12, 2017
Better understanding of the dose-toxicity relationship is critical for safe dose escalation to improve local control in late-stage cervical cancer radiotherapy. In this study, we introduced a convolutional neural network (CNN) model to analyze rectum...
Rectum Feasibility Studies Organs at Risk Radiotherapy Planning, Computer-Assisted Neural Networks, Computer Brachytherapy Radiotherapy Dosage Retrospective Studies Female Humans Uterine Cervical Neoplasms
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Evaluation of a Machine-Learning Algorithm for Treatment Planning in Prostate Low-Dose-Rate Brachytherapy.

International journal of radiation oncology, biology, physics Nov 27, 2016
PURPOSE: This work presents the application of a machine learning (ML) algorithm to automatically generate high-quality, prostate low-dose-rate (LDR) brachytherapy treatment plans. The ML algorithm can mimic characteristics of preoperative treatment ...
Treatment Outcome Prostatic Neoplasms Radiotherapy Planning, Computer-Assisted Brachytherapy Algorithms Reproducibility of Results Sensitivity and Specificity Male Radiotherapy Dosage Dose-Response Relationship, Radiation Radiometry Radiotherapy, Image-Guided Humans Machine Learning
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Exploring Value From the Patient's Perspective Between Modern Radiation Therapy Modalities for Localized Prostate Cancer.

International journal of radiation oncology, biology, physics Nov 24, 2016
PURPOSE: Patients' perspectives on their treatment experiences have not been compared between modern radiation modalities for localized prostate cancer. We evaluated treatment regret and patients' perceptions of their treatment experiences to better ...
Brachytherapy Radiotherapy Dosage Radiotherapy, Intensity-Modulated Radiosurgery Decision Making Prostatic Neoplasms Watchful Waiting Patient Satisfaction Middle Aged Surveys and Questionnaires Follow-Up Studies Emotions Humans Aged, 80 and over Aged Adult Male
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An ultrasound image navigation robotic prostate brachytherapy system based on US to MRI deformable image registration method.

Hellenic journal of nuclear medicine Nov 8, 2016
OBJECTIVE: This paper describes an ultrasound image navigation robotic prostate brachytherapy system. It uses a 2D ultrasound (US) probe rigidly fixed to a robotic needle insertion mechanism. Combined with the US probe registration and image registra...
Multimodal Imaging Robotics Equipment Design Ultrasonography, Interventional Image Enhancement Reproducibility of Results Sensitivity and Specificity Magnetic Resonance Imaging Brachytherapy Equipment Failure Analysis Radiotherapy, Image-Guided
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Outcomes Associated With 3 Treatment Schedules of High-Dose-Rate Brachytherapy Monotherapy for Favorable-Risk Prostate Cancer.

International journal of radiation oncology, biology, physics Nov 10, 2015
PURPOSE: We report the outcomes associated with 3 high-dose-rate (HDR) brachytherapy regimens used as monotherapy for favorable-risk prostate cancer.
Dose Fractionation, Radiation Male Radiation Injuries Middle Aged Humans Urogenital System Gastrointestinal Tract Time Factors Aged Brachytherapy Follow-Up Studies Aged, 80 and over Prostatic Neoplasms Urination Disorders Chronic Disease Adult Risk Prostate-Specific Antigen Acute Disease Neoplasm Grading
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SBRT and HDR brachytherapy produce lower PSA nadirs and different PSA decay patterns than conventionally fractionated IMRT in patients with low- or intermediate-risk prostate cancer.

Practical radiation oncology Nov 10, 2015
PURPOSE: To compare patterns of prostate-specific antigen (PSA) response following stereotactic body radiation therapy (SBRT), high-dose-rate (HDR) brachytherapy, and conventionally fractionated intensity modulated radiation therapy (IMRT) in patient...
Aged, 80 and over Male Middle Aged Humans Aged Prostatic Neoplasms Prostate-Specific Antigen Brachytherapy Radiotherapy, Intensity-Modulated
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Is modern external beam radiotherapy with androgen deprivation therapy still a viable alternative for prostate cancer in an era of robotic surgery and brachytherapy: a comparison of Australian series.

Journal of medical imaging and radiation oncology Jan 15, 2015
INTRODUCTION: We compare the results of modern external-beam radiotherapy (EBRT), using combined androgen deprivation and dose-escalated intensity-modulated radiotherapy with MRI-CT fusion and daily image guidance with fiducial markers (DE-IG-IMRT), ...
Androgen Antagonists Disease-Free Survival Radiotherapy, Conformal Brachytherapy Australia Robotics Prostatic Neoplasms Surgery, Computer-Assisted Chemoradiotherapy Retrospective Studies Risk Factors Aged Aged, 80 and over Middle Aged Prevalence Treatment Outcome Survival Rate Male Humans
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A customizable P hydrogel applicator for brachytherapy of skin hemangioma based on machine learning and 3D-printing.

Journal of materials chemistry. B May 14, 2025
Skin hemangioma is a tumor originating from skin blood vessels, which often occurs in infants and children. Brachytherapy with the P-based radionuclide applicator is an effective non-invasive therapeutic method. However, the inordinance of lesions is...
Humans Printing, Three-Dimensional Acrylic Resins Hydrogels Brachytherapy Machine Learning Hemangioma Skin Neoplasms Animals Mice
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Advancing patient care: Machine learning models for predicting grade 3+ toxicities in gynecologic cancer patients treated with HDR brachytherapy.

PloS one Jan 1, 2025
BACKGROUND: Gynecological cancers are among the most prevalent cancers in women worldwide. Brachytherapy, often used as a boost to external beam radiotherapy, is integral to treatment. Advances in computation, algorithms, and data availability have p...
Support Vector Machine Genital Neoplasms, Female Brachytherapy Radiotherapy Dosage Female Aged Adult Humans Middle Aged Machine Learning Retrospective Studies
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