AIMC Topic: Cell Line
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Extraction optimization, purification and characterization of polysaccharides from the seed coat of black soybean.
PloS one
Dec 21, 2017
In this study, the extraction of water-soluble polysaccharides from the seed coat of black soybean (BSCP) was investigated and optimized. A response surface methodology based on a Box-Behnken design (BBD) was used to optimize the extraction condition...
Chemical characterization and wound healing property of a β-D-glucan from edible mushroom Piptoporus betulinus.
International journal of biological macromolecules
Dec 20, 2017
A water-soluble β-D-glucan was obtained from fruiting bodies of Piptoporus betulinus, by hot aqueous extraction followed by freeze-thawing procedure and dialysis. Its molar mass distribution and conformational behavior in solution was assessed by siz...
Antibacterial mechanisms of a novel type picosecond laser-generated silver-titanium nanoparticles and their toxicity to human cells.
International journal of nanomedicine
Dec 20, 2017
In this study, we explored the antibacterial mechanisms for a novel type of Ag-TiO compound nanoparticles (NPs) produced from an Ag-TiO alloy using a picosecond laser and evaluated the toxicity of the Ag-TiO NPs to a range of human cell types. Transm...
Multi-Objective Optimization Algorithm to Discover Condition-Specific Modules in Multiple Networks.
Molecules (Basel, Switzerland)
Dec 14, 2017
The advances in biological technologies make it possible to generate data for multiple conditions simultaneously. Discovering the condition-specific modules in multiple networks has great merit in understanding the underlying molecular mechanisms of ...
Ginsenoside Rg1 protects human renal tubular epithelial cells from lipopolysaccharide-induced apoptosis and inflammation damage.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Dec 11, 2017
Ginsenoside Rg1, one of the most notable active components of Panax ginseng, has been widely reported to exert anti-inflammatory actions. This study aimed to reveal whether ginsenoside Rg1 also exhibits beneficial roles against lipopolysaccharide (LP...
Cell Migration Assays
Ginsenosides
Nephritis
Phosphatidylinositol 3-Kinases
Proto-Oncogene Proteins c-akt
Protective Agents
Reproducibility of Results
Analysis of Variance
Blotting, Western
Enzyme-Linked Immunosorbent Assay
Kidney Tubules
Anti-Inflammatory Agents
Apoptosis
Lipopolysaccharides
Cell Line
Reactive Oxygen Species
Epithelial Cells
Cell Survival
Humans
Cytokines
Development of an artificial neural network model for risk assessment of skin sensitization using human cell line activation test, direct peptide reactivity assay, KeratinoSens™ and in silico structure alert parameter.
Journal of applied toxicology : JAT
Dec 10, 2017
It is important to predict the potential of cosmetic ingredients to cause skin sensitization, and in accordance with the European Union cosmetic directive for the replacement of animal tests, several in vitro tests based on the adverse outcome pathwa...
Construction of a system using a deep learning algorithm to count cell numbers in nanoliter wells for viable single-cell experiments.
Scientific reports
Dec 4, 2017
For single-cell experiments, it is important to accurately count the number of viable cells in a nanoliter well. We used a deep learning-based convolutional neural network (CNN) on a large amount of digital data obtained as microscopic images. The tr...
Cytoprotective Effects of Cell-Permeable Bifunctional Antioxidant Enzyme, GST-TAT-SOD, against Cisplatin-Induced Cell Damage.
Oxidative medicine and cellular longevity
Nov 30, 2017
GST-TAT-SOD, a cell-permeable bifunctional antioxidant enzyme, is a potential selective radioprotector. This study aimed to investigate the cytoprotective activity of GST-TAT-SOD against cisplatin-induced damage. The current study showed that cisplat...
Changes in polyphenol composition and bioactivity of the native Chilean white strawberry (Fragaria chiloensis spp. chiloensis f. chiloensis) after in vitro gastrointestinal digestion.
Food research international (Ottawa, Ont.)
Nov 8, 2017
The Chilean white strawberry (Fragaria chiloensis spp. chiloensis f. chiloensis) is a semi-domesticated strawberry with high polyphenol content and antioxidant activity occurring in southern Chile. The aim of this work was to compare the composition ...
Using machine learning algorithms to identify genes essential for cell survival.
BMC bioinformatics
Oct 3, 2017
BACKGROUND: With the explosion of data comes a proportional opportunity to identify novel knowledge with the potential for application in targeted therapies. In spite of this huge amounts of data, the solutions to treating complex disease is elusive....
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