AIMC Topic: Diabetes Mellitus, Experimental
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Bacterial endosymbiont inhabiting leaves and their antioxidant and antidiabetic potential.
Journal of complementary & integrative medicine
Dec 22, 2020
OBJECTIVES: Research on endosymbionts is emerging globally and is considered as a potential source of bioactive phytochemicals. The present study examines the antioxidant and antidiabetic of the endophytic crude extract isolated from leaves.
An innovative method for screening and evaluating the degree of diabetic retinopathy and drug treatment based on artificial intelligence algorithms.
Pharmacological research
Jun 2, 2020
Current methods of evaluating the degree of diabetic retinopathy are highly subjective and have no quantitative standard. To objectively evaluate the slight changes in tissue structure during the early stage of retinal diseases, a subjective interpre...
Diabetes Mellitus, Type 1
Hypoglycemic Agents
Predictive Value of Tests
Drugs, Chinese Herbal
Animals
Diabetic Retinopathy
Diabetes Mellitus, Type 2
Male
Mice
Early Diagnosis
Severity of Illness Index
Rats, Wistar
Deep Learning
Diabetes Mellitus, Experimental
Retinal Ganglion Cells
Retina
Pattern Recognition, Automated
Microscopy
Retinal Vessels
Image Interpretation, Computer-Assisted
Novel indolizine derivatives lowers blood glucose levels in streptozotocin-induced diabetic rats: A histopathological approach.
Pharmacological reports : PR
Nov 28, 2018
BACKGROUND: Diabetes mellitus is a deadly disorder in human which induce chronic complications. The streptozotocin (STZ)-induced diabetes in rat is the most common animal model of human diabetes. The present study investigated the effects of novel in...
Neural network-based model predictive control for type 1 diabetic rats on artificial pancreas system.
Medical & biological engineering & computing
Aug 1, 2018
Artificial pancreas system (APS) is a viable option to treat diabetic patients. Researchers, however, have not conclusively determined the best control method for APS. Due to intra-/inter-variability of insulin absorption and action, an individualize...
Cupuaçu extract reduces nitrosative stress and modulates inflammatory mediators in the kidneys of experimental diabetes.
Clinical nutrition (Edinburgh, Scotland)
Dec 26, 2017
BACKGROUND & AIMS: We have previously reported an increased nitrosative stress in the kidneys of diabetic animals, which was reduced by an antioxidant probiotic. The present study evaluated whether the extract of cupuaçu (EC), an antioxidant compound...
Two-way learning with one-way supervision for gene expression data.
BMC bioinformatics
Mar 4, 2017
BACKGROUND: A family of parsimonious Gaussian mixture models for the biclustering of gene expression data is introduced. Biclustering is accommodated by adopting a mixture of factor analyzers model with a binary, row-stochastic factor loadings matrix...
Integration of multi-omics data and machine learning to identify antioxidant biomarkers in type 1 diabetes.
Free radical biology & medicine
Aug 16, 2025
The identification of biomarkers for early diagnosis and monitoring the progression of Type 1 Diabetes (T1DM) is essential for improving disease management. This study integrates multi-omics data with machine learning to identify antioxidant stress p...
Exploration of hypoglycemic effect of an extract from leaves of a plant from Tunisian pharmacopeia: ().
African health sciences
Dec 1, 2019
BACKGROUND AND OBJECTIVES: A lot of research has been directed towards medicinal plants which are considered as a source of multiple phytotherapic substances endowed with hypoglycemic activities that could be used to treat diabetes and its complicati...
[rhPDGF-BB promotes migration of bone marrow stromal stem cells in diabetic rats].
Shanghai kou qiang yi xue = Shanghai journal of stomatology
Dec 1, 2018
PURPOSE: To evaluate the effect of different concentrations of rhPDGF-BB on bone marrow stromal stem cells(BMSCs) migration in diabetic rat, and related mechanisms of SDF-1 and its G-protein conjugated receptor regulation, provide a theoretical basis...
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