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Diabetes Mellitus, Experimental

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Exploration of hypoglycemic effect of an extract from leaves of a plant from Tunisian pharmacopeia: ().

African health sciences
BACKGROUND AND OBJECTIVES: A lot of research has been directed towards medicinal plants which are considered as a source of multiple phytotherapic substances endowed with hypoglycemic activities that could be used to treat diabetes and its complicati...

[rhPDGF-BB promotes migration of bone marrow stromal stem cells in diabetic rats].

Shanghai kou qiang yi xue = Shanghai journal of stomatology
PURPOSE: To evaluate the effect of different concentrations of rhPDGF-BB on bone marrow stromal stem cells(BMSCs) migration in diabetic rat, and related mechanisms of SDF-1 and its G-protein conjugated receptor regulation, provide a theoretical basis...

Novel indolizine derivatives lowers blood glucose levels in streptozotocin-induced diabetic rats: A histopathological approach.

Pharmacological reports : PR
BACKGROUND: Diabetes mellitus is a deadly disorder in human which induce chronic complications. The streptozotocin (STZ)-induced diabetes in rat is the most common animal model of human diabetes. The present study investigated the effects of novel in...

Cupuaçu extract reduces nitrosative stress and modulates inflammatory mediators in the kidneys of experimental diabetes.

Clinical nutrition (Edinburgh, Scotland)
BACKGROUND & AIMS: We have previously reported an increased nitrosative stress in the kidneys of diabetic animals, which was reduced by an antioxidant probiotic. The present study evaluated whether the extract of cupuaçu (EC), an antioxidant compound...

Two-way learning with one-way supervision for gene expression data.

BMC bioinformatics
BACKGROUND: A family of parsimonious Gaussian mixture models for the biclustering of gene expression data is introduced. Biclustering is accommodated by adopting a mixture of factor analyzers model with a binary, row-stochastic factor loadings matrix...

Neural network-based model predictive control for type 1 diabetic rats on artificial pancreas system.

Medical & biological engineering & computing
Artificial pancreas system (APS) is a viable option to treat diabetic patients. Researchers, however, have not conclusively determined the best control method for APS. Due to intra-/inter-variability of insulin absorption and action, an individualize...