AIMC Topic: Doxorubicin

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Multifunctional surface microrollers for targeted cargo delivery in physiological blood flow.

Science robotics May 20, 2020
Mobile microrobots offer great promise for minimally invasive targeted medical theranostic applications at hard-to-access regions inside the human body. The circulatory system represents the ideal route for navigation; however, blood flow impairs pro...
Cell Line, Tumor Robotics Equipment Design Drug Delivery Systems Antineoplastic Agents Hemodynamics Surface Properties Biomimetic Materials Magnetics Multifunctional Nanoparticles Motion Doxorubicin Microtechnology Humans Precision Medicine
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[RETROPERITONEAL LIPOSARCOMA WITH MULTIPLE RECURRENCE OF LUNG METASTASES TREATED BY MULTIMODAL THERAPY CENTERING ON THE OPERATION: A CASE REPORT].

Nihon Hinyokika Gakkai zasshi. The japanese journal of urology Jan 1, 2018
A 34-year-old man presented with scrotal pain and slight fever. The scrotal pain was improved by the treatment of antibiotics, but the slight fever remained and an abdominal protuberance appeared. Computed tomography showed a 22 cm abdominal tumor wi...
Liposarcoma Retroperitoneal Neoplasms Thoracoscopy Treatment Outcome Surgical Procedures, Operative Lymph Node Excision Etoposide Pneumonectomy Time Factors Ifosfamide Neoplasm Recurrence, Local Humans Lung Neoplasms Combined Modality Therapy Antineoplastic Combined Chemotherapy Protocols Adult Doxorubicin Male
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Development and validation of a LC-FL method for the simultaneous determination of doxorubicin and celecoxib in nanoparticulate fixed dose combination (NanoFDC).

Die Pharmazie Oct 1, 2017
An isocratic reversed phase HPLC method for the simultaneous determination of doxorubicine (DOX) and celecoxib (CXB) out of a nanoparticulate fixed dose combination (NanoFDC) was developed and validated. Linearity of the results was demonstrated from...
Celecoxib Drug Combinations Reproducibility of Results Chromatography, High Pressure Liquid Cyclooxygenase 2 Inhibitors Limit of Detection Nanoparticles Doxorubicin Antibiotics, Antineoplastic Antineoplastic Combined Chemotherapy Protocols
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Redox-Responsive Amphipathic Dextran Nanomicelles for Solid Tumor Therapy.

Journal of biomedical nanotechnology Dec 1, 2016
A disulfide bond containing deoxycholic acid-grafted dextran (Dex-SSDCA) was successfully prepared for drug delivery. The Dex-SSDCA polymers can self-assemble into nanomicelles at concentrations below 56 g/mL and encapsulate doxorubicin (DOX) effecti...
Antineoplastic Agents Cell Line, Tumor Mice Apoptosis Dextrans Cell Survival Dithiothreitol Humans Doxorubicin Nanoparticles Animals Drug Carriers Micelles Mice, Nude Male MCF-7 Cells Oxidation-Reduction Xenograft Model Antitumor Assays
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Robotic printing and drug testing of 384-well tumor spheroids.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Aug 1, 2015
A major impediment to anti-cancer drug development is the lack of a reliable and inexpensive tumor model to test the efficacy of candidate compounds. This need has emerged due to the insufficiency of widely-used monolayer cultures to predict drug eff...
Equipment Design Polymers Doxorubicin High-Throughput Screening Assays Spheroids, Cellular Triple Negative Breast Neoplasms Humans Drug Screening Assays, Antitumor Female Robotics Antineoplastic Agents
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Doxorubicin enhances (131)I-rituximab induced cell death in Raji cells.

Journal of cancer research and therapeutics Jan 1, 2015
AIM: There are various therapeutic modalities of treatment for non-Hodgkin's lymphoma, but with certain limitations, hence, investigating the scope of combined therapeutic approach.
Drug Synergism Tumor Cells, Cultured Rituximab Poly(ADP-ribose) Polymerases Burkitt Lymphoma Radiation-Sensitizing Agents Radiopharmaceuticals Doxorubicin Iodine Radioisotopes Apoptosis Blotting, Western Flow Cytometry Humans Signal Transduction Antineoplastic Combined Chemotherapy Protocols RNA, Messenger Cell Proliferation
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Untethered magnetic millirobot for targeted drug delivery.

Biomedical microdevices Jan 1, 2015
This paper reports the design and development of a novel millimeter-sized robotic system for targeted therapy. The proposed medical robot is conceived to perform therapy in relatively small diameter body canals (spine, urinary system, ovary, etc.), a...
Robotics Equipment Design Doxorubicin Humans Cell Line, Tumor Urinary Bladder Neoplasms Magnetic Fields Lab-On-A-Chip Devices Equipment Failure Analysis Infusion Pumps, Implantable Miniaturization Delayed-Action Preparations Magnets
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