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Recurrent Neural Networks for Early Detection of Heart Failure From Longitudinal Electronic Health Record Data: Implications for Temporal Modeling With Respect to Time Before Diagnosis, Data Density, Data Quantity, and Data Type.

Circulation. Cardiovascular quality and outcomes Oct 15, 2019
BACKGROUND: We determined the impact of data volume and diversity and training conditions on recurrent neural network methods compared with traditional machine learning methods.
California Vital Signs Heart Failure Early Diagnosis Smoking Alcohol Drinking Reproducibility of Results Risk Factors Male Diagnosis, Computer-Assisted Incidence Time Factors Primary Health Care Longitudinal Studies Predictive Value of Tests Humans Neural Networks, Computer Machine Learning Electronic Health Records Female
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Atrial Fibrillation Burden Signature and Near-Term Prediction of Stroke: A Machine Learning Analysis.

Circulation. Cardiovascular quality and outcomes Oct 15, 2019
BACKGROUND: Atrial fibrillation (AF) increases the risk of stroke 5-fold and there is rising interest to determine if AF severity or burden can further risk stratify these patients, particularly for near-term events. Using continuous remote monitorin...
Humans Neural Networks, Computer Machine Learning Aged Aged, 80 and over Male Middle Aged Risk Assessment Prognosis Retrospective Studies Electronic Health Records Female Risk Factors Predictive Value of Tests Administrative Claims, Healthcare Signal Processing, Computer-Assisted Telemetry Stroke Veterans Health Services Atrial Fibrillation Proof of Concept Study Diagnosis, Computer-Assisted Time Factors Logistic Models United States
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Zoster patients on earth and astronauts in space share similar immunologic profiles.

Life sciences in space research Oct 14, 2019
BACKGROUND: On long-duration spaceflight, most astronauts experience persistent immune dysregulation and the reactivation of latent herpesviruses, including varicella zoster virus (VZV). To understand the clinical risk of these perturbations to astro...
DNA, Viral Saliva Adult Astronauts Herpesvirus 3, Human Humans Herpes Zoster T-Lymphocytes Cytokines Male Female Middle Aged Aged Lymphocyte Activation
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Hippocampal segmentation for brains with extensive atrophy using three-dimensional convolutional neural networks.

Human brain mapping Oct 14, 2019
Hippocampal volumetry is a critical biomarker of aging and dementia, and it is widely used as a predictor of cognitive performance; however, automated hippocampal segmentation methods are limited because the algorithms are (a) not publicly available,...
Image Interpretation, Computer-Assisted Humans Hippocampus Neural Networks, Computer Neuroimaging Atrophy Female Aged Male Dementia Magnetic Resonance Imaging
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Cascaded deep convolutional encoder-decoder neural networks for efficient liver tumor segmentation.

Medical hypotheses Oct 14, 2019
Liver and hepatic tumor segmentation remains a challenging problem in Computer Tomography (CT) images analysis due to its shape variation and vague boundary. The general hypothesis says that deep learning methods produce improved results on medical i...
Datasets as Topic Preoperative Care Software Design Diagnosis, Computer-Assisted Algorithms Deep Learning Humans Tomography, X-Ray Computed Liver Neoplasms Female Image Processing, Computer-Assisted Male Early Detection of Cancer
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Granger causality analysis in combination with directed network measures for classification of MS patients and healthy controls using task-related fMRI.

Computers in biology and medicine Oct 13, 2019
Several studies have already assessed brain network variations in multiple sclerosis (MS) patients and healthy controls (HCs). The underlying neural system's functioning is apparently too complicated, however. Therefore, the neural time series' analy...
Brain Mapping Male Humans Multiple Sclerosis Support Vector Machine Brain Nerve Net Female Magnetic Resonance Imaging Models, Neurological Adult
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Design and development of a robotic predator as a stimulus in conditioned place aversion for the study of the effect of ethanol and citalopram in zebrafish.

Behavioural brain research Oct 12, 2019
Zebrafish are becoming a species of choice in psychopharmacology, laying a promising path to refined pharmacological manipulations and high-throughput behavioral phenotyping. The field of robotics has the potential to accelerate progress along this p...
Association Citalopram Selective Serotonin Reuptake Inhibitors Central Nervous System Depressants Ethanol Robotics Equipment Design Zebrafish Behavior, Animal Fear Conditioning, Psychological Predatory Behavior Female Avoidance Learning Animals Spatial Behavior Male
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A comparative study of machine learning classifiers for risk prediction of asthma disease.

Photodiagnosis and photodynamic therapy Oct 12, 2019
Asthma is a chronic disease characterized by wheezing, chest tightening and difficulty in breathing due to inflammation of lung airways. Early risk prediction of asthma is crucial for proper and effective management. This study presents the use of ma...
Humans Neural Networks, Computer Machine Learning Female Aged Adult Asthma Support Vector Machine Male Predictive Value of Tests Middle Aged Case-Control Studies Spectrum Analysis, Raman
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Identification and Quantification of Cardiovascular Structures From CCTA: An End-to-End, Rapid, Pixel-Wise, Deep-Learning Method.

JACC. Cardiovascular imaging Oct 11, 2019
OBJECTIVES: This study designed and evaluated an end-to-end deep learning solution for cardiac segmentation and quantification.
Humans Prospective Studies Female Reproducibility of Results Aged Radiographic Image Interpretation, Computer-Assisted Registries Heart Diseases Male Middle Aged Deep Learning Predictive Value of Tests Coronary Angiography Multidetector Computed Tomography Computed Tomography Angiography
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The ethical, legal and social implications of using artificial intelligence systems in breast cancer care.

Breast (Edinburgh, Scotland) Oct 11, 2019
Breast cancer care is a leading area for development of artificial intelligence (AI), with applications including screening and diagnosis, risk calculation, prognostication and clinical decision-support, management planning, and precision medicine. W...
Humans Artificial Intelligence Decision Support Systems, Clinical Australia Early Detection of Cancer Precision Medicine Technology Assessment, Biomedical Prognosis Female Breast Neoplasms Risk Assessment
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