Alzheimer's disease (AD), the most prevalent neurodegenerative disorder, is marked by the accumulation of amyloid-β (Aβ) plaques. Although cerebral Aβ positron emission tomography (Aβ-PET) remains the gold standard for assessing cerebral Aβ burden, i...
Lateral flow immunoassay (LFA) remains one of the most widely used point-of-care testing (POCT) platforms for disease diagnosis, food safety assessment, and environmental monitoring. However, traditional LFAs typically require up to 30 min and offer ...
ConspectusEngineered nanomaterials (ENMs) have revolutionized biomedicine, energy, and environmental remediation due to their unique physicochemical properties. However, these properties are not static; they evolve dynamically as ENMs interact with r...
Endoluminal stent implantation is a common intervention strategy for treating obstructive lesions, but conventional delivery systems struggle to reach deep, tortuous ducts. To overcome this limitation, we present a magnetically controlled microrobot ...
Robotic micromanipulation has advanced cellular probing, yet achieving precise, minimally invasive intracellular operations without fluorescent labeling remains challenging. Fluorescent techniques often cause photodamage and cytotoxicity and interfer...
Lipid nanoparticles (LNPs) are a promising nonviral delivery system for gene-editing proteins, but optimal formulations remain underexplored. Unlike messenger RNA-based approaches, ribonucleoprotein delivery enables immediate genome editing without r...
BACKGROUND: Type 2 diabetes (T2D) and its vascular complications, including diabetic retinopathy (DR), are escalating in prevalence globally, with disproportionately high prevalence in Middle Eastern populations, where genetic predispositions and lif...
BACKGROUND: Serum lipase levels are crucial biomarkers in acute pancreatitis (AP), yet their dynamic patterns and prognostic implications remain incompletely understood. This study aimed to identify distinct lipase trajectory phenotypes and evaluate ...
OBJECTIVE: This study investigated the relationship between estimated glucose disposal rate (eGDR), aging acceleration (AgeAccel), and mortality in adults diagnosed with cardiovascular-kidney-metabolic (CKM) stages 1 to 4.
BACKGROUND: Rapid diagnostic tests (RDTs) have improved malaria case management by enabling point-of-care confirmation of infection, particularly in low-resource settings. In addition to clinical use, RDT results recorded in health facility registers...
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