IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Apr 16, 2025
The coordination of muscles in human locomotion is commonly understood as the integration of motor modules known as muscle synergies. Recent research has delved into the adaptation of muscle synergies during the acquisition of new motor skills. Howev...
BACKGROUND: Emerging evidence underscores smooth muscle hyperplasia and hypertrophy, rather than fibrosis, as the defining characteristics of fibrostenotic lesions in Crohn disease (CD). However, non-invasive methods for quantifying these muscular ch...
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
Apr 15, 2025
INTRODUCTION: External radiation therapy for bladder cancer requires large planning target volumes (PTVs) due to the daily anatomy of the bladder. Online adaptive radiotherapy (oART) can reduce the PTV by considering daily anatomical changes.
We present a comprehensive, quantitative model of the allosteric molecular mechanisms of selective cholesterol (CHL) uptake and delivery by the StarD4 protein - an intracellular cholesterol trafficking protein that facilitates the crucial non-vesicul...
Journal of molecular graphics & modelling
Apr 15, 2025
Ankyrins are proteins widely distributed in nature that mediate protein‒protein interactions. Owing to their outstanding stability and ability to recognize targets, ankyrins have been used as therapeutic and diagnostic tools in several diseases, incl...
Hyperlipidemia, a major risk factor for cardiovascular diseases, is associated with limitations in clinical lipid-lowering medications. Drug repurposing strategies expedite the research process and mitigate development costs, offering an innovative a...
Medical & biological engineering & computing
Apr 15, 2025
The aim of this study was to develop a deep learning method for analyzing CT images with varying doses and qualities, aiming to categorize lung lesions into nodules and non-nodules. This study utilized the lung nodule analysis 2016 challenge dataset....
The high lethality and infectiousness of coronaviruses, particularly SARS-Cov-2, pose a significant threat to human society. Understanding coronaviruses, especially the interactions between these viruses and humans, is crucial for mitigating the coro...
INTRODUCTION: Older adult breast cancer (OABC) patients (≥ 65 years) frequently experience poorer prognoses compared to younger adults, attributed to complex tumor biology and age-related factors. The present study employs a multiomics approach combi...
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