AIMC Topic: Inflammation

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Effects of xenoestrogens in human M1 and M2 macrophage migration, cytokine release, and estrogen-related signaling pathways.

Environmental toxicology
Bisphenol A (BPA), bis(2-ethylhexyl)phthalate (DEHP) and di(n-butyl)phthalate (DBP) are environmental estrogens that have been associated with a wide range of adverse health outcomes for which inflammation has also been hypothesized as a potentially ...

A machine learning heuristic to identify biologically relevant and minimal biomarker panels from omics data.

BMC genomics
BACKGROUND: Investigations into novel biomarkers using omics techniques generate large amounts of data. Due to their size and numbers of attributes, these data are suitable for analysis with machine learning methods. A key component of typical machin...

Machine learning-driven prediction of readmission risk in heart failure patients with diabetes: synergistic assessment of inflammatory and metabolic biomarkers.

International journal of cardiology
BACKGROUND: Heart failure (HF) and diabetes mellitus (DM) frequently coexist, exacerbating disease progression and increasing hospital readmission risk. Accurate prediction of readmission in HF patients with DM remains a clinical challenge. This stud...

Machine Learning With Ingredient-Level Food Trees Reveals Contributors to Systemic Inflammation Among Adults in the National Health and Nutrition Examination Survey, 2001-2010 and 2015-2018.

Journal of the Academy of Nutrition and Dietetics
BACKGROUND: Methods for modeling the relationship between self-reported 24-hour dietary recalls and health outcomes are traditionally based on nutrients and/or dietary patterns. Machine learning (ML), combined with hierarchical representations of die...

Machine learning prediction of thrombolysis efficacy using hs-CRP and inflammatory markers in stroke.

Medicine
The aim of this study was to investigate the relationship between serum ultrasensitive C-reactive protein (hs-CRP) levels and stroke incidence and to assess its potential role in decision-making for thrombolytic therapy in stroke. Given that hs-CRP i...

Ptgs2+ CPTC Function as a "Force-Immune Axis" by Responding to Acupuncture and Mediating M2 Macrophage Activation for Anti-Inflammatory Effects.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Recent advancements have highlighted the imperative for cytological exploration of fascial tissues. Telocytes, specialized interstitial cells found in connective tissues such as fascia, have garnered significant attention. Our study explored the cell...

Inflammatory biomarkers as predictors for unlocking antidepressant efficacy: Assessing predictive value and risk stratification in major depressive disorder in a prospective longitudinal study.

Journal of affective disorders
BACKGROUND: Major depressive disorder (MDD) is characterized by significant heterogeneity in treatment response, with inflammation hypothesized to play a role in its pathophysiology. Peripheral inflammatory biomarkers, such as the neutrophil-to-lymph...

Association between long-term exposure of polystyrene microplastics and exacerbation of seizure symptoms: Evidence from multiple approaches.

Ecotoxicology and environmental safety
Microplastics are tiny plastic particles originating from both commercial product manufacturing and the degradation of larger plastic materials. These particles pose significant risks to environmental and animal health. A growing body of evidence hig...