BACKGROUND: We aimed to create a Machine learning (ML) model using patient demographic, clinical and pathological data for prediction of overall survival in patients treated with radical cystectomy (RC). Secondly, we evaluated whether inflammatory ma...
BACKGROUND: Interactions between inflammation and sleep disorders are increasingly recognized; however, limited research comprehensively evaluates the association between multiple inflammatory indicators and sleep disorders.
Type 2 diabetes mellitus (T2DM) is a severe metabolic disorder in which pancreatic injury plays a pivotal role in disease progression. Tanshinone IIA (TanIIA), a bioactive compound extracted from Salvia miltiorrhiza, has shown therapeutic potential i...
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that increases the risk of cardiovascular complications. The atherogenic index of plasma (AIP) is a risk marker for T2DM and cardiovascular disease on the basis of lipid profiles. T2DM an...
BACKGROUND: Vascular inflammation plays a critical role in the development of coronary artery disease (CAD). Measurement of coronary inflammation from coronary computed tomography angiography (CCTA) using the perivascular fat attenuation index (FAI) ...
Our study explores signatures for Crohn's disease (CD) and Ulcerative Colitis (UC) reflecting an interplay between the intestinal microbiota, systemic inflammation, and plasma bile acid homeostasis. For this, 1,257 individuals scheduled for colonosco...
Journal of health, population, and nutrition
Oct 6, 2025
INTRODUCTION: The study investigates the relationship between blood lipid components and metabolic disorders, specifically high-density lipoprotein cholesterol (HDL-C), which is crucial for cardiovascular health. It uses logistic regression (LR), dec...
Pancreatic cancer is an aggressive disease with a dense fibrotic stroma and is often accompanied by chronic inflammation. Peritumoral inflammation is typically viewed as a reaction to nearby tumor growth. Here, we report that the inflamed pancreatic ...
Nuclear receptors (NRs) are a superfamily of ligand-activated transcription factors that regulate gene expression in response to metabolic, hormonal, and environmental signals. These receptors play a critical role in metabolic homeostasis, inflammati...
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