AIMC Topic: Inflammation

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Deep learning for fetal inflammatory response diagnosis in the umbilical cord.

Placenta
INTRODUCTION: Inflammation of the umbilical cord can be seen as a result of ascending intrauterine infection or other inflammatory stimuli. Acute fetal inflammatory response (FIR) is characterized by infiltration of the umbilical cord by fetal neutro...

Artificial Intelligence-Enabled Quantitative Assessment and Intervention for Heart Inflammation Model Organoids.

Angewandte Chemie (International ed. in English)
Inflammation plays a crucial role in progression of cardiovascular diseases (CVDs); thus, the discovery of rapid and precise analytical tools to assess inflammation related to CVDs is highly desirable for their diagnosis and therapeutic discovery. Ho...

Molecular features and diagnostic modeling of synovium- and IPFP-derived OA macrophages in the inflammatory microenvironment via scRNA-seq and machine learning.

Journal of orthopaedic surgery and research
BACKGROUND: Osteoarthritis (OA) is the leading cause of degenerative joint disease, with total joint replacement as the only definitive cure. However, no disease-modifying therapy is currently available. Inflammation and fibrosis in the infrapatellar...

Machine learning based association between inflammation indicators (NLR, PLR, NPAR, SII, SIRI, and AISI) and all-cause mortality in arthritis patients with hypertension: NHANES 1999-2018.

Frontiers in public health
BACKGROUND: This study aimed to evaluate the relationship between CBC-derived inflammatory markers (NLR, PLR, NPAR, SII, SIRI, and AISI) and all-cause mortality (ACM) risk in arthritis (AR) patients with hypertensive (HTN) using data from the NHANES.

Improved MRI detection of inflammation-induced changes in bone marrow microstructure in mice: a machine learning-enhanced T2 distribution analysis.

European radiology experimental
BACKGROUND: We investigated inflammation-induced changes in femoral hematopoietic bone marrow using advanced magnetic resonance imaging (MRI) techniques, including T2-weighted imaging, scalar T2 mapping, and machine learning-enhanced T2 distribution ...

Infection and Inflammation in Nuclear Medicine Imaging: The Role of Artificial Intelligence.

Seminars in nuclear medicine
Infectious and inflammatory diseases represent a global challenge. Delayed diagnosis and treatment lead to death, disabilities and impairment of the quality of life. The detection of low-grade inflammation and occult infections remains challenging. N...

Identification of novel inflammatory response-related biomarkers in patients with ischemic stroke based on WGCNA and machine learning.

European journal of medical research
BACKGROUND: Ischemic stroke (IS) is one of the most common causes of disability in adults worldwide. This study aimed to identify key genes related to the inflammatory response to provide insights into the mechanisms and management of IS.

Defining lipedema's molecular hallmarks by multi-omics approach for disease prediction in women.

Metabolism: clinical and experimental
Lipedema is a chronic disease in females characterized by pathologic subcutaneous adipose tissue expansion and hitherto remains without druggable targets. In this observational study, we investigated the molecular hallmarks of lipedema using an unbia...

Comparison of ChatGPT-4o, Google Gemini 1.5 Pro, Microsoft Copilot Pro, and Ophthalmologists in the management of uveitis and ocular inflammation: A comparative study of large language models.

Journal francais d'ophtalmologie
PURPOSE: The aim of this study was to compare the latest large language models (LLMs) ChatGPT-4o, Google Gemini 1.5 Pro and Microsoft Copilot Pro developed by three different companies, with each other and with a group of ophthalmologists, to reveal ...

Artificial intelligence-powered prediction of AIM-2 inflammasome sequences using transformers and graph attention networks in periodontal inflammation.

Scientific reports
Periodontal inflammation is a chronic condition affecting the tissues surrounding teeth. Initiated by dental plaque, it triggers an immune response leading to tissue destruction. The AIM-2 inflammasome regulates this response, and understanding its p...