Liver international : official journal of the International Association for the Study of the Liver
Jun 1, 2025
BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is linked to cognitive decline and dementia risk. We aimed to investigate the association between MASLD and brain ageing and explore the role of low-grade inflammation.
Rapid communications in mass spectrometry : RCM
May 30, 2025
Gancao Fuzi decoction (GCFZT) is a traditional Chinese formula, which has been commonly used in clinical practice to treat inflammatory diseases. However, the active substance of GCFZT in the treatment of inflammation is not fully clarified. In this ...
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
May 15, 2025
Vimentin, an abundant intracellular cytoskeletal protein, is secreted into the extracellular space, where it can amplify tissue destruction in inflammatory diseases. The mechanisms by which inflammation promotes the release of extracellular vimentin ...
BACKGROUND: Malnutrition, influenced by inflammation, is associated with muscle depletion and body composition changes. This study aimed to evaluate muscle mass and quality using Artificial Intelligence (AI)-enhanced ultrasonography in patients with ...
BACKGROUND: Dysregulated programmed cell death pathways mechanistically contribute to hepatic inflammation and fibrogenesis in non-alcoholic steatohepatitis (NASH). Identification of cell death genes may offer insights into diagnostic and therapeutic...
Translational vision science & technology
May 1, 2025
PURPOSE: Quantitative assessment of inflammation is critical for the accurate diagnosis and effective management of uveitis. This study aims to introduce a novel three-dimensional vision transformer approach using anterior segment optical coherence t...
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
May 1, 2025
OBJECTIVE: To outline immune-cell infiltration and identify diagnostic genes for atherosclerosis (AS) to better understand the potential molecular processes involved in AS development.
Journal of biomolecular structure & dynamics
May 1, 2025
Activation of NLRP3 (NOD-like receptor family, pyrin domain-containing protein 3) has been associated with multiple chronic pathologies, including diabetes, atherosclerosis, and rheumatoid arthritis. Moreover, histone deacetylases (HDACs), specifical...
BACKGROUND: Coronary artery plaque rupture (PR) is closely associated with immune-inflammatory responses. The systemic inflammatory index (SII) and the systemic inflammatory response index (SIRI) have shown potential in predicting the occurrence of P...
Parkinson's disease (PD) is a common and debilitating neurodegenerative disorder. The inflammatory response is essential in the pathogenesis and progression of PD. The goal of this study is to combine bioinformatics and machine learning to screen for...
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