AIMC Topic: Kidney Diseases
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Pharmacokinetics and Safety of Elotuzumab Combined With Lenalidomide and Dexamethasone in Patients With Multiple Myeloma and Various Levels of Renal Impairment: Results of a Phase Ib Study.
Clinical lymphoma, myeloma & leukemia
Dec 21, 2015
INTRODUCTION: The present study evaluated the pharmacokinetics and safety of elotuzumab, a humanized IgG1 monoclonal antibody against signaling lymphocyte activation molecule-F7, combined with lenalidomide and dexamethasone, in patients with multiple...
Antineoplastic Combined Chemotherapy Protocols
Treatment Outcome
Kidney Function Tests
Antibodies, Monoclonal, Humanized
Kidney Diseases
Multiple Myeloma
Thalidomide
Lenalidomide
Neoplasm Staging
Cytogenetic Analysis
Dexamethasone
Retreatment
Adult
Male
Middle Aged
Severity of Illness Index
Humans
Female
Aged
Aged, 80 and over
Impact of renal impairment on platelet reactivity and clinical outcomes during chronic dual antiplatelet therapy following coronary stenting.
European heart journal. Cardiovascular pharmacotherapy
Dec 17, 2015
AIMS: Clinical utilization of dual antiplatelet therapy (DAPT) in patients with renal impairment (RI) following percutaneous coronary interventions (PCI) represents an urgent, unmet need choosing optimal agents, duration of treatment, and potential d...
A Soft Computing Approach to Kidney Diseases Evaluation.
Journal of medical systems
Aug 27, 2015
Kidney renal failure means that one's kidney have unexpectedly stopped functioning, i.e., once chronic disease is exposed, the presence or degree of kidney dysfunction and its progression must be assessed, and the underlying syndrome has to be diagno...
Robot-assisted laparoscopic management of duplex renal anomaly: Comparison of surgical outcomes to traditional pure laparoscopic and open surgery.
Journal of pediatric urology
Aug 17, 2015
INTRODUCTION: Surgical management of duplex renal anomaly (DRA) is complex because of individual anatomic variation, competing priorities of vesicoureteral reflux (VUR) and ureteral obstruction present in the same child, the varied differential funct...
Lack of association between anemia and renal disease progression in Chinese patients with type 2 diabetes.
Journal of diabetes investigation
Jun 3, 2015
AIMS/INTRODUCTION: Anemia has a close interaction with renal dysfunction in diabetes patients. More proof is still awaited on the relationship between anemia and the progression of renal disease in this population.
Comparing the efficacy and safety between robotic-assisted versus open pyeloplasty in children: a systemic review and meta-analysis.
World journal of urology
Mar 10, 2015
OBJECTIVE: This manuscript is mainly to systemically review the published reports that compared the efficacy and safety of robotic-assisted (RP) versus open pyeloplasty (OP) in children with ureteropelvic junction obstruction (UPJO).
PhenoMiner: a quantitative phenotype database for the laboratory rat, Rattus norvegicus. Application in hypertension and renal disease.
Database : the journal of biological databases and curation
Jan 28, 2015
Rats have been used extensively as animal models to study physiological and pathological processes involved in human diseases. Numerous rat strains have been selectively bred for certain biological traits related to specific medical interests. Recent...
Molecule-Responsive SERS Sensors for Urine Diagnosis of Kidney Diseases Enhanced by Neural Networks.
Analytical chemistry
Jul 1, 2025
Early diagnosis of kidney disease is crucial for treatment and prognosis. Compared with kidney biopsy, a noninvasive urine-based diagnosis method of kidney disease can be more convenient and less painful for patients. Urine is closely associated with...
MACHINE LEARNING AND SHOCK INDICES-DERIVED SCORE FOR PREDICTING CONTRAST-INDUCED NEPHROPATHY IN ACUTE CORONARY SYNDROME PATIENTS.
Shock (Augusta, Ga.)
Jul 1, 2025
Background: Contrast-induced nephropathy (CIN) is a serious complication following acute coronary syndrome (ACS), leading to increased morbidity and mortality. Machine learning (ML), combined with parameters such as shock indices, can potentially imp...
An explainable adaptive channel weighting-based deep convolutional neural network for classifying renal disorders in computed tomography images.
Computers in biology and medicine
Jun 1, 2025
Renal disorders are a significant public health concern and a cause of mortality related to renal failure. Manual diagnosis is subjective, labor-intensive, and depends on the expertise of nephrologists in renal anatomy. To improve workflow efficiency...
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