BACKGROUND: High intraoperative blood pressure variability (HIBPV) is significantly associated with postoperative adverse complications. However, practical tools to characterize perioperative factors associated with HIBPV remain limited. This study a...
BACKGROUND: Ultra-early detection of brain injury biomarkers within the critical first hour post-injury remains a major clinical challenge in mild traumatic brain injury (mTBI) management. Conventional platforms (e.g., ELISA) suffer from limited sens...
Psychological resilience is influenced by both psychological and biological factors. However, the potential of using DNA methylation (DNAm) probes and brain imaging variables to predict psychological resilience remains unclear. This study aimed to in...
Primary large B-cell lymphomas of immune-privileged sites, including primary central nervous system lymphoma (PCNSL) and primary testicular lymphoma (PTL), exhibit distinct clinicopathologic features contributing to aggressive behavior and immune eva...
Exposure to fine particulate matter (PM) from solid-fuel combustion is a major determinant of global morbidity and mortality. However, variations in exposure remain uncertain across many high-risk populations. This work describes personal PM exposure...
BACKGROUND: Intensive care unit (ICU)-acquired weakness (ICUAW) is a prevalent complication in critically ill patients, marked by symmetrical respiratory and limb muscle weakness, which adversely affects long-term outcomes. Early identification of hi...
Journal of neuroengineering and rehabilitation
Jul 24, 2025
BACKGROUND AND PURPOSE: The brain-computer interface-based soft robotic glove (BCI-SRG) holds promise for upper limb rehabilitation in subacute stroke patients, yet its efficacy and neural mechanisms are unclear. This study aimed to investigate the t...
BACKGROUND: Comprehensive analysis of single-cell transcriptome and chromatin accessibility will contribute to interpret the heterogeneity of acute myeloid leukemia (AML). We hypothesize that integrating single-cell transcriptomic and chromatin acces...
BMC medical informatics and decision making
Jul 24, 2025
BACKGROUND: Coronary artery disease (CAD) remains a leading cause of global mortality, with stroke constituting a significant complication among patients undergoing coronary revascularization procedures, such as percutaneous coronary intervention (PC...
BACKGROUND: Pancreatic cellular heterogeneity is fundamental to systemic metabolic regulation, yet its pathological remodeling in diabetes remains poorly characterized.
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