AIMC Topic: Mice

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[Effect of moxa-cone moxibustion at lung's back- points and front- points on Th17/Treg balance in mice with asthma].

Zhongguo zhen jiu = Chinese acupuncture & moxibustion
OBJECTIVE: To observe the effect of moxa-cone moxibustion at lung's back- points and front- points on the expression of helper T lymphocyte 17 (Th 17)/regulatory T lymphocyte (Treg) in mice with asthma, and to explore the possible mechanism of moxa-c...

[Determination of dacarbazine in the urine of mice with melanoma by high performance liquid chromatography].

Se pu = Chinese journal of chromatography
Dacarbazine (DTIC) is a first-line chemotherapy drug that is widely used in clinical practice for malignant melanoma. DTIC is metabolized by the liver . Some drugs are excreted in urine in the form of a prototype. Hence, DTIC in urine can be monitore...

Fennel fortified diet: New perspective with regard to fertility and sex hormones.

Pakistan journal of pharmaceutical sciences
The objective of this study was to evaluate the effect of Foeniculum vulgare (FV) on fertility of mice and on serum sex hormone values of rats and rabbits. We used powdered form of Foeniculum vulgare seed and added it to food of mice, rats and rabbit...

3D computational cannula fluorescence microscopy enabled by artificial neural networks.

Optics express
Computational cannula microscopy (CCM) is a high-resolution widefield fluorescence imaging approach deep inside tissue, which is minimally invasive. Rather than using conventional lenses, a surgical cannula acts as a lightpipe for both excitation and...

A Systematic Evaluation of Interneuron Morphology Representations for Cell Type Discrimination.

Neuroinformatics
Quantitative analysis of neuronal morphologies usually begins with choosing a particular feature representation in order to make individual morphologies amenable to standard statistics tools and machine learning algorithms. Many different feature rep...

Comparative study of antibacterial activity between Schiff base nicotinic hydrazide derivative and its silver architected nanoparticles with atomic force microscopic study of bacterial cell wall.

Pakistan journal of pharmaceutical sciences
The threat of multi-drug resistant bacterial pathogens evokes researchers to synthesized safe and effective chemotherapeutic agents for nano-drug delivery system. In current study, Schiff base of nicotinic hydrazide(NHD) and its silver nanoparticles(...

Formulation and evaluation of antioxidant and antityrosinase activity of Polygonum amplexicaule herbal gel.

Pakistan journal of pharmaceutical sciences
Medicinal plants are long been used for pharmaceutical and cosmetic industry. Among medicinal plants, Polygonum amplexicaule of family polygonaceae has traditional use in medicines and skin care. P. amplexicaule belongs to genus Polygonum that contai...

DeepCLIP: predicting the effect of mutations on protein-RNA binding with deep learning.

Nucleic acids research
Nucleotide variants can cause functional changes by altering protein-RNA binding in various ways that are not easy to predict. This can affect processes such as splicing, nuclear shuttling, and stability of the transcript. Therefore, correct modeling...

Elucidating the interaction dynamics between microswimmer body and immune system for medical microrobots.

Science robotics
The structural design parameters of a medical microrobot, such as the morphology and surface chemistry, should aim to minimize any physical interactions with the cells of the immune system. However, the same surface-borne design parameters are also c...

Uncovering the key dimensions of high-throughput biomolecular data using deep learning.

Nucleic acids research
Recent advances in high-throughput single-cell RNA-seq have enabled us to measure thousands of gene expression levels at single-cell resolution. However, the transcriptomic profiles are high-dimensional and sparse in nature. To address it, a deep lea...