AIMC Topic: Middle Aged

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The Role of GDF-15 in Heart Failure Patients With Chronic Kidney Disease.

The Canadian journal of cardiology
BACKGROUND: Growth differentiation factor-15 (GDF-15) is a stress-inducible cytokine and member of the transforming growth factor-β cytokine superfamily that refines prognostic assessment in subgroups of patients with heart failure (HF). We evaluated...

Local Infiltration Analgesia With Liposomal Bupivacaine Improves Early Outcomes After Total Knee Arthroplasty: 24-Hour Data From the PILLAR Study.

The Journal of arthroplasty
BACKGROUND: Enhanced postoperative care pathways have shifted total knee arthroplasty (TKA) to outpatient and short-stay settings, placing greater emphasis on predischarge outcomes. In this study, we report prespecified secondary and tertiary end poi...

Prediction and evaluation of the severity of acute respiratory distress syndrome following severe acute pancreatitis using an artificial neural network algorithm model.

HPB : the official journal of the International Hepato Pancreato Biliary Association
BACKGROUND: To predict the risk and severity of acute respiratory distress syndrome (ARDS) following severe acute pancreatitis (SAP) by artificial neural networks (ANNs) model.

Association of time to colonoscopy after a positive fecal test result and fecal hemoglobin concentration with risk of advanced colorectal neoplasia.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
BACKGROUND: We evaluated the risk of advanced colorectal neoplasia (ACRN) and colorectal cancer (CRC) according to time to colonoscopy after positive fecal immunochemical test (FIT), fecal hemoglobin concentration, and combination of both.

Constipation and risk of death and cardiovascular events.

Atherosclerosis
BACKGROUND AND AIMS: Constipation is one of the most frequent symptoms encountered in daily clinical practice and is implicated in the development of atherosclerosis, potentially through altered gut microbiota. However, little is known about its asso...

Aortic remodeling after hybrid provisional extension to induce complete attachment aortic repair of chronic residual type I aortic dissection.

The Journal of thoracic and cardiovascular surgery
OBJECTIVES: Our objective was to examine the role of the provisional extension to induce complete attachment (PETTICOAT) aortic dissection repair technique with bare metal stents (BMSs) in abdominal remodeling of residual DeBakey type I aortic dissec...

Total Knee Arthroplasty Is Safe and Successful in Patients With Klippel-Trénaunay Syndrome.

The Journal of arthroplasty
BACKGROUND: Klippel-Trénaunay syndrome (KTS) is a severe vascular malformation that can lead to hypertrophic osteoarthritis. Total knee arthroplasty (TKA) performed in extremities affected with KTS is challenging given the high-risk vascular consider...

Survival outcome prediction in cervical cancer: Cox models vs deep-learning model.

American journal of obstetrics and gynecology
BACKGROUND: Historically, the Cox proportional hazard regression model has been the mainstay for survival analyses in oncologic research. The Cox proportional hazard regression model generally is used based on an assumption of linear association. How...

HIV is associated with endothelial activation despite ART, in a sub-Saharan African setting.

Neurology(R) neuroimmunology & neuroinflammation
OBJECTIVE: To study the relationship between endothelial dysfunction, HIV infection, and stroke in Malawians.