AIMC Topic: Middle Aged

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Development of a novel machine learning model to automate vertebral column segmentation utilizing biplanar full-body imaging.

The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: Degenerative scoliosis (DS) is a common spinal disorder among adults, characterized by lateral curvature of the spine. Recent advancements in biplanar full-body imaging, a low-dose and weight-bearing X-ray modality, facilitate saf...

Explainable artificial intelligence for prediction of refractory ulcerative colitis: analysis of a Japanese Nationwide Registry.

Annals of medicine
OBJECTIVE: Ulcerative colitis (UC) is a chronic inflammatory bowel disease for which remission is dependent on corticosteroid (CS) treatment. The diversity of disease pathophysiology necessitates optimal case-specific treatment selection. This study ...

A machine learning model for mortality prediction in patients with severe fever with thrombocytopenia syndrome: a prospective, multicenter cohort study.

Emerging microbes & infections
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that imposes a considerable medical burden. In this study, we enrolled 1,606 SFTS patients, developed and validated machine learning models for mortality prediction,...

Development and external validation of a machine learning model for cardiac valve calcification early screening in dialysis patients: a multicenter study.

Renal failure
BACKGROUND: Cardiac valve calcification (CVC) is common in dialysis patients and associated with increased cardiovascular risk. However, early screening has been limited by cost concerns. This study aimed to develop and validate a machine learning mo...

Analyzing factors influencing hospitalization costs for five common cancers in China using neural network models.

Journal of medical economics
BACKGROUND: Malignant tumors are a major global health crisis, causing 25% of deaths in China, with lung, liver, thyroid, breast, and colon cancers being the most common. Understanding the factors influencing hospitalization costs for these cancers i...

Development and validation of multi-center serum creatinine-based models for noninvasive prediction of kidney fibrosis in chronic kidney disease.

Renal failure
OBJECTIVE: Kidney fibrosis is a key pathological feature in the progression of chronic kidney disease (CKD), traditionally diagnosed through invasive kidney biopsy. This study aimed to develop and validate a noninvasive, multi-center predictive model...

A machine learning approach to risk-stratification of gastric cancer based on tumour-infiltrating immune cell profiles.

Annals of medicine
BACKGROUND: Gastric cancer (GC) is a highly heterogeneous disease, and the response of patients to clinical treatment varies substantially. There is no satisfactory strategy for predicting curative effects to date. We aimed to explore a new method fo...

Machine learning algorithms for diabetic kidney disease risk predictive model of Chinese patients with type 2 diabetes mellitus.

Renal failure
BACKGROUND: Diabetic kidney disease (DKD) is a common and serious complication of diabetic mellitus (DM). More sensitive methods for early DKD prediction are urgently needed. This study aimed to set up DKD risk prediction models based on machine lear...

Risk prediction for acute kidney disease and adverse outcomes in patients with chronic obstructive pulmonary disease: an interpretable machine learning approach.

Renal failure
BACKGROUND: Little is known about acute kidney injury (AKI) and acute kidney disease (AKD) in patients with chronic obstructive pulmonary disease (COPD) and COPD mortality based on the acute/subacute renal injury. This study develops machine learning...