AIMC Topic: Middle Aged
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A novel UHPLC-HRMS method for simultaneous determination of 20 amino metabolites and proteins in lymphoma patients' cells and serum.
Scientific reports
Jul 1, 2025
Highly sensitive and selective monitoring of amino metabolites such as glutamine, arginine, tryptophan and related proteins played significant roles in early diagnosis and warning of lymphoma. But those limited abundance and lacked chromophore group ...
Brain structural features with functional priori to classify Parkinson's disease and multiple system atrophy using diagnostic MRI.
Scientific reports
Jul 1, 2025
Clinical two-dimensional (2D) MRI data has seen limited application in the early diagnosis of Parkinson's disease (PD) and multiple system atrophy (MSA) due to quality limitations, yet its diagnostic and therapeutic potential remains underexplored. T...
Radiomics analysis based on dynamic contrast-enhanced MRI for predicting early recurrence after hepatectomy in hepatocellular carcinoma patients.
Scientific reports
Jul 1, 2025
This study aimed to develop a machine learning model based on Magnetic Resonance Imaging (MRI) radiomics for predicting early recurrence after curative surgery in patients with hepatocellular carcinoma (HCC).A retrospective analysis was conducted on ...
Machine learning and transformer models for prediction of postoperative pneumonia risk in patients with lower limb fractures.
Scientific reports
Jul 1, 2025
Postoperative pneumonia, a prevalent complication arising from lower limb fracture surgery, can significantly prolong hospitalization periods and elevate mortality rates. Consequently, early prevention and identification of this condition are crucial...
Mitochondrial haplogroup A2 is associated with increased COVID-19 mortality in an admixed Brazilian population.
Scientific reports
Jul 1, 2025
Mitochondria play a crucial role in cellular respiration and immune responses. Mitochondrial DNA (mtDNA) haplogroups and variants have been associated with various diseases, including COVID-19. This study analyzed complete mtDNA sequences from 467 Br...
Enrichment of extracellular vesicles using Mag-Net for the analysis of the plasma proteome.
Nature communications
Jul 1, 2025
Extracellular vesicles (EVs) in plasma are composed of exosomes, microvesicles, and apoptotic bodies. We report a plasma EV enrichment strategy using magnetic beads called Mag-Net. Proteomic interrogation of this plasma EV fraction enables the detect...
Predicting car accident severity in Northwest Ethiopia: a machine learning approach leveraging driver, environmental, and road conditions.
Scientific reports
Jul 1, 2025
Road traffic accidents (RTAs) in Northwest Ethiopia, a region with a fatality rate of 32.2 per 100,000 residents, pose a critical public health challenge exacerbated by infrastructural deficits and environmental hazards. This study leverages machine ...
Single pulse electrical stimulation of the medial thalamic surface induces narrower high gamma band activities in the sensorimotor cortex.
Scientific reports
Jul 1, 2025
The human thalamus projects nerve fibers to all cortical regions and propagates epileptic activity. However, opportunities to directly record thalamic and cortical neural activities simultaneously are extremely limited and their electrophysiological ...
Auto-Segmentation via deep-learning approaches for the assessment of flap volume after reconstructive surgery or radiotherapy in head and neck cancer.
Scientific reports
Jul 1, 2025
Reconstructive flap surgery aims to restore the substance and function losses associated with tumor resection. Automatic flap segmentation could allow quantification of flap volume and correlations with functional outcomes after surgery or post-opera...
Predicting diabetic peripheral neuropathy through advanced plantar pressure analysis: a machine learning approach.
Scientific reports
Jul 1, 2025
Diabetic foot Ulceration (DFU) is a severe complication of diabetic foot syndrome, often leading to amputation. In patients with neuropathy, ulcer formation is facilitated by elevated plantar tissue stress under insensate feet. This study presents a ...
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