AIMC Topic: Neoplasm Metastasis
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Machine Learning and Mechanistic Modeling for Prediction of Metastatic Relapse in Early-Stage Breast Cancer.
JCO clinical cancer informatics
Mar 1, 2020
PURPOSE: For patients with early-stage breast cancer, predicting the risk of metastatic relapse is of crucial importance. Existing predictive models rely on agnostic survival analysis statistical tools (eg, Cox regression). Here we define and evaluat...
Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body.
Cell
Dec 12, 2019
Reliable detection of disseminated tumor cells and of the biodistribution of tumor-targeting therapeutic antibodies within the entire body has long been needed to better understand and treat cancer metastasis. Here, we developed an integrated pipelin...
Machine-Learning and Stochastic Tumor Growth Models for Predicting Outcomes in Patients With Advanced Non-Small-Cell Lung Cancer.
JCO clinical cancer informatics
Sep 1, 2019
PURPOSE: The prediction of clinical outcomes for patients with cancer is central to precision medicine and the design of clinical trials. We developed and validated machine-learning models for three important clinical end points in patients with adva...
Prognosis
Lung Neoplasms
Treatment Outcome
Carcinoma, Non-Small-Cell Lung
Humans
Machine Learning
Algorithms
Tumor Burden
Neoplasm Metastasis
Molecular Targeted Therapy
Kaplan-Meier Estimate
Stochastic Processes
Randomized Controlled Trials as Topic
Neoplasm Staging
Models, Biological
Combined Modality Therapy
Morphology-based prediction of cancer cell migration using an artificial neural network and a random decision forest.
Integrative biology : quantitative biosciences from nano to macro
Dec 19, 2018
Metastasis is the cause of death in most patients of breast cancer and other solid malignancies. Identification of cancer cells with highly migratory capability to metastasize relies on markers for epithelial-to-mesenchymal transition (EMT), a proces...
Lab-On-A-Chip Devices
Neoplasms
Deep Learning
Cell Line, Tumor
Single-Cell Analysis
Epithelial-Mesenchymal Transition
Models, Biological
Neoplasm Metastasis
Mice
Cell Movement
Female
Reproducibility of Results
Breast Neoplasms
Animals
Humans
Neural Networks, Computer
Algorithms
Decision Support Techniques
Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.
Cell
Apr 5, 2018
Cancer progression involves the gradual loss of a differentiated phenotype and acquisition of progenitor and stem-cell-like features. Here, we provide novel stemness indices for assessing the degree of oncogenic dedifferentiation. We used an innovati...
Machine learning based cancer detection using various image modalities.
Computer methods and programs in biomedicine
Mar 1, 2018
[Intramedullary nail combined with auxiliary plate and bone cement in treatment of pathologic fracture of extremities caused by metastatic tumors].
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
Dec 15, 2017
OBJECTIVE: To explore the application of intramedullary nail fixation combined with auxiliary plate and bone cement in the palliative treatment of pathologic fracture of extremities caused by metastatic tumors.
Hematopoiesis is prognostic for toxicity and survival of Radium treatment in patients with metastatic castration-resistant prostate cancer.
Hellenic journal of nuclear medicine
Jan 1, 2017
OBJECTIVE: We evaluated the impact of pre-therapeutic hematopoiesis on survival, hematotoxicity (HT) and number of Radium (Ra) treatments in patients with metastatic castration-resistant prostate cancer.
Effect of hypoparathyroid on bone mineral density of lumber spine in postmenopausal women with differentiated thyroid cancinoma.
Hellenic journal of nuclear medicine
Jan 1, 2017
OBJECTIVE: To investigate the effect of hypoparathyroid on bone mineral density in postmenopausal women with differentiated thyroid carcinoma (DTC).
Everolimus in heavily pretreated metastatic breast cancer: Is real world experience different?
Indian journal of cancer
Jan 1, 2016
BACKGROUND: Drugs targeting mammalian target of rapamycin signaling pathway have been recently approved for treatment of hormone receptor (HR) positive metastatic breast cancer (MBC). However, there is lack of real world data from India on the use of...
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