AIMC Topic: Neoplasms

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BrcaSeg: A Deep Learning Approach for Tissue Quantification and Genomic Correlations of Histopathological Images.

Genomics, proteomics & bioinformatics
Epithelial and stromal tissues are components of the tumor microenvironment and play a major role in tumor initiation and progression. Distinguishing stroma from epithelial tissues is critically important for spatial characterization of the tumor mic...

[Artificial intelligence, radiomics and pathomics to predict response and survival of patients treated with radiations].

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Artificial intelligence approaches in medicine are more and more used and are extremely promising due to the growing number of data produced and the variety of data they allow to exploit. Thus, the computational analysis of medical images in particul...

Recent advances in drug repurposing using machine learning.

Current opinion in chemical biology
Drug repurposing aims to find new uses for already existing and approved drugs. We now provide a brief overview of recent developments in drug repurposing using machine learning alongside other computational approaches for comparison. We also highlig...

Prioritizing and characterizing functionally relevant genes across human tissues.

PLoS computational biology
Knowledge of genes that are critical to a tissue's function remains difficult to ascertain and presents a major bottleneck toward a mechanistic understanding of genotype-phenotype links. Here, we present the first machine learning model-FUGUE-combini...

DeepProg: an ensemble of deep-learning and machine-learning models for prognosis prediction using multi-omics data.

Genome medicine
Multi-omics data are good resources for prognosis and survival prediction; however, these are difficult to integrate computationally. We introduce DeepProg, a novel ensemble framework of deep-learning and machine-learning approaches that robustly pre...

Predicting pathogenic non-coding SVs disrupting the 3D genome in 1646 whole cancer genomes using multiple instance learning.

Scientific reports
Over the past years, large consortia have been established to fuel the sequencing of whole genomes of many cancer patients. Despite the increased abundance in tools to study the impact of SNVs, non-coding SVs have been largely ignored in these data. ...

A fusion decision system to identify and grade malnutrition in cancer patients: Machine learning reveals feasible workflow from representative real-world data.

Clinical nutrition (Edinburgh, Scotland)
BACKGROUND AND AIMS: Most nutritional assessment tools are based on pre-defined questionnaires or consensus guidelines. However, it has been postulated that population data can be used directly to develop a solution for assessing malnutrition. This s...

A deep look into radiomics.

La Radiologia medica
Radiomics is a process that allows the extraction and analysis of quantitative data from medical images. It is an evolving field of research with many potential applications in medical imaging. The purpose of this review is to offer a deep look into ...

Augmented intelligence to predict 30-day mortality in patients with cancer.

Future oncology (London, England)
An augmented intelligence tool to predict short-term mortality risk among patients with cancer could help identify those in need of actionable interventions or palliative care services. An algorithm to predict 30-day mortality risk was developed us...