AIMC Topic: Oxidative Stress

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Preparation, characterization, and protective effects of carbon dots against oxidative damage induced by LPS in IPEC-J2 cells.

Frontiers in cellular and infection microbiology
This study aimed to prepare carbon dots (GF-CDs) and examine their efficacy in mitigating oxidative stress and apoptosis in intestinal porcine epithelial cells from the jejunum (IPEC-J2 cells) induced by lipopolysaccharide (LPS). The GF-CDs were syn...

Cross-disease transcriptomic analysis reveals DOK3 and PAPOLA as therapeutic targets for neuroinflammatory and tumorigenic processes.

Frontiers in immunology
OBJECTIVE: Subarachnoid hemorrhage (SAH) and tumorigenesis share numerous biological complexities; nevertheless, the specific gene expression profiles and underlying mechanisms remain poorly understood. This study aims to identify differentially expr...

Exploring the Psychological and Physiological Effects of Operating a Telenoid: The Preliminary Assessment of a Minimal Humanoid Robot for Mediated Communication.

Sensors (Basel, Switzerland)
BACKGROUND: As the Internet of Things (IoT) expands, it enables new forms of communication, including interactions mediated by teleoperated robots like avatars. While extensive research exists on the effects of these devices on communication partners...

Comparison of machine learning methods for Predicting 3-Year survival in elderly esophageal squamous cancer patients based on oxidative stress.

BMC cancer
BACKGROUND: Oxidative stress process plays a key role in aging and cancer; however, currently, there is paucity of machine-learning model studies investigating the relationship between oxidative stress and prognosis of elderly patients with esophagea...

The Bioprotective Effects of Marigold Tea Polyphenols on Obesity and Oxidative Stress Biomarkers in High-Fat-Sugar Diet-Fed Rats.

Cardiovascular therapeutics
The research is aimed at exploring the potential of marigold petal tea (MPT), rich in polyphenol contents, against oxidative stress and obesity in a rat model following a high-fat-sugar diet (HFSD). The MPT was prepared through the customary method...

Carbon dot unravels accumulation of triterpenoid in Evolvulus alsinoides hairy roots culture by stimulating growth, redox reactions and ANN machine learning model prediction of metabolic stress response.

Plant physiology and biochemistry : PPB
Evolvulus alsinoides, a therapeutically valuable shrub can provide consistent supply of secondary metabolites (SM) with pharmaceutical significance. Nonetheless, because of its short life cycle, fresh plant material for research and medicinal diagnos...

Machine learning analysis of oxidative stress-related phenotypes for specific gene screening in ovarian cancer.

Environmental toxicology
BACKGROUND: Oxidative stress serves a crucial role in tumor development. However, the relationship between ovarian cancer and oxidative stress remains unknown. We aimed to create an oxidative stress-related prognostic signature to enhance the prognos...

APOD: A biomarker associated with oxidative stress in acute rejection of kidney transplants based on multiple machine learning algorithms and animal experimental validation.

Transplant immunology
BACKGROUND: Oxidative stress is an unavoidable process in kidney transplantation and is closely related to the development of acute rejection after kidney transplantation. This study aimed to investigate the biomarkers associated with oxidative stres...

Detecting depression severity using weighted random forest and oxidative stress biomarkers.

Scientific reports
This study employs machine learning to detect the severity of major depressive disorder (MDD) through binary and multiclass classifications. We compared models that used only biomarkers of oxidative stress with those that incorporate sociodemographic...

Hierarchical multi-task deep learning-assisted construction of human gut microbiota reactive oxygen species-scavenging enzymes database.

mSphere
In the process of oxygen reduction, reactive oxygen species (ROS) are generated as intermediates, including superoxide anion (O), hydrogen peroxide (HO), and hydroxyl radicals (OH). ROS can be destructive, and an imbalance between oxidants and antiox...