AIMC Topic: Pancreatic Neoplasms
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Radiogenomics for predicting p53 status, PD-L1 expression, and prognosis with machine learning in pancreatic cancer.
British journal of cancer
Jul 21, 2020
BACKGROUND: Radiogenomics is an emerging field that integrates "Radiomics" and "Genomics". In the current study, we aimed to predict the genetic information of pancreatic tumours in a simple, inexpensive, and non-invasive manner, using cancer imaging...
Robot-assisted combined pancreatectomy/hepatectomy for metastatic pancreatic acinar cell carcinoma: case report and review of the literature.
Clinical journal of gastroenterology
Jun 25, 2020
Acinar cell carcinoma (ACC) of the pancreas is a rare neoplasm with less aggressive behavior than ductal carcinoma. As a result, surgical resection for metastatic ACC is a therapeutic option which can result in long-term survival. There is a paucity ...
Oral microbiome-systemic link studies: perspectives on current limitations and future artificial intelligence-based approaches.
Critical reviews in microbiology
May 21, 2020
In the past decade, there has been a tremendous increase in studies on the link between oral microbiome and systemic diseases. However, variations in study design and confounding variables across studies often lead to inconsistent observations. In th...
Preliminary clinical application of the robot-assisted CT-guided irreversible electroporation ablation for the treatment of pancreatic head carcinoma.
The international journal of medical robotics + computer assisted surgery : MRCAS
May 6, 2020
BACKGROUND: To evaluate the feasibility and safety of a robot-guided irreversible electroporation (IRE) ablation system for the treatment of pancreatic head carcinoma.
Network modeling of patients' biomolecular profiles for clinical phenotype/outcome prediction.
Scientific reports
Feb 27, 2020
Methods for phenotype and outcome prediction are largely based on inductive supervised models that use selected biomarkers to make predictions, without explicitly considering the functional relationships between individuals. We introduce a novel netw...
Predicted Prognosis of Patients with Pancreatic Cancer by Machine Learning.
Clinical cancer research : an official journal of the American Association for Cancer Research
Jan 28, 2020
PURPOSE: Pancreatic cancer remains a disease of high mortality despite advanced diagnostic techniques. Mucins (MUC) play crucial roles in carcinogenesis and tumor invasion in pancreatic cancers. MUC1 and MUC4 expression are related to the aggressive ...
Machine Learning and Network Analyses Reveal Disease Subtypes of Pancreatic Cancer and their Molecular Characteristics.
Scientific reports
Jan 27, 2020
Given that the biological processes governing the oncogenesis of pancreatic cancers could present useful therapeutic targets, there is a pressing need to molecularly distinguish between different clinically relevant pancreatic cancer subtypes. To add...
Deep pancreas segmentation with uncertain regions of shadowed sets.
Magnetic resonance imaging
Jan 24, 2020
Pancreas segmentation is a challenging task in medical image analysis especially for the patients with pancreatic cancer. First, the images often have poor contrast and blurred boundaries. Second, there exist large variations in gray scale, texture, ...
Propofol affects the growth and metastasis of pancreatic cancer via ADAM8.
Pharmacological reports : PR
Dec 20, 2019
BACKGROUND: Anesthesia is a major component of surgery and recently considered an important regulator of cell phenotypes. Here we aimed to investigate propofol, an anesthesia drug, in suppressing pancreatic cancer (PDAC), focusing on A disintegrin an...
ADAM Proteins
Mice, SCID
Apoptosis
Membrane Proteins
Neoplasm Invasiveness
Matrix Metalloproteinase 2
Cell Proliferation
Humans
Pancreatic Neoplasms
Xenograft Model Antitumor Assays
Propofol
Neoplasm Metastasis
Animals
Matrix Metalloproteinase 9
Cell Movement
MAP Kinase Signaling System
Antineoplastic Agents
Cell Line, Tumor
Radiomics in stratification of pancreatic cystic lesions: Machine learning in action.
Cancer letters
Oct 17, 2019
Pancreatic cystic lesions (PCLs) are well-known precursors of pancreatic cancer. Their diagnosis can be challenging as their behavior varies from benign to malignant disease. Precise and timely management of malignant pancreatic cysts might prevent t...
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