AIMC Topic: Prognosis

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Distant metastasis time to event analysis with CNNs in independent head and neck cancer cohorts.

Scientific reports
Deep learning models based on medical images play an increasingly important role for cancer outcome prediction. The standard approach involves usage of convolutional neural networks (CNNs) to automatically extract relevant features from the patient's...

Integrated multi-omics analysis of ovarian cancer using variational autoencoders.

Scientific reports
Cancer is a complex disease that deregulates cellular functions at various molecular levels (e.g., DNA, RNA, and proteins). Integrated multi-omics analysis of data from these levels is necessary to understand the aberrant cellular functions accountab...

Predicting gastric cancer outcome from resected lymph node histopathology images using deep learning.

Nature communications
N-staging is a determining factor for prognostic assessment and decision-making for stage-based cancer therapeutic strategies. Visual inspection of whole-slides of intact lymph nodes is currently the main method used by pathologists to calculate the ...

Proposing a machine-learning based method to predict stillbirth before and during delivery and ranking the features: nationwide retrospective cross-sectional study.

BMC pregnancy and childbirth
BACKGROUND: Stillbirth is defined as fetal loss in pregnancy beyond 28 weeks by WHO. In this study, a machine-learning based method is proposed to predict stillbirth from livebirth and discriminate stillbirth before and during delivery and rank the f...

Quantitative PET in the 2020s: a roadmap.

Physics in medicine and biology
Positron emission tomography (PET) plays an increasingly important role in research and clinical applications, catalysed by remarkable technical advances and a growing appreciation of the need for reliable, sensitive biomarkers of human function in h...

An imageomics and multi-network based deep learning model for risk assessment of liver transplantation for hepatocellular cancer.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
INTRODUCTION: Liver transplantation (LT) is an effective treatment for hepatocellular carcinoma (HCC), the most common type of primary liver cancer. Patients with small HCC (<5 cm) are given priority over others for transplantation due to clinical al...

Precision medicine and machine learning towards the prediction of the outcome of potential celiac disease.

Scientific reports
Potential Celiac Patients (PCD) bear the Celiac Disease (CD) genetic predisposition, a significant production of antihuman transglutaminase antibodies, but no morphological changes in the small bowel mucosa. A minority of patients (17%) showed clinic...

A new machine learning approach for predicting likelihood of recurrence following ablation for atrial fibrillation from CT.

BMC medical imaging
OBJECTIVE: To investigate left atrial shape differences on CT scans of atrial fibrillation (AF) patients with (AF+) versus without (AF-) post-ablation recurrence and whether these shape differences predict AF recurrence.

The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types.

EBioMedicine
BACKGROUND: The development of a reactive tumour stroma is a hallmark of tumour progression and pronounced tumour stroma is generally considered to be associated with clinical aggressiveness. The variability between tumour types regarding stroma frac...

Predicting Parkinson's disease trajectory using clinical and neuroimaging baseline measures.

Parkinsonism & related disorders
INTRODUCTION: Predictive biomarkers of Parkinson's Disease progression are needed to expedite neuroprotective treatment development and facilitate prognoses for patients. This work uses measures derived from resting-state functional magnetic resonanc...