AIMC Topic: Prognosis

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Deep learning informed multimodal fusion of radiology and pathology to predict outcomes in HPV-associated oropharyngeal squamous cell carcinoma.

EBioMedicine
BACKGROUND: We aim to predict outcomes of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC), a subtype of head and neck cancer characterized with improved clinical outcome and better response to therapy. Pathology an...

Machine learning-based model for predicting all-cause mortality in severe pneumonia.

BMJ open respiratory research
BACKGROUND: Severe pneumonia has a poor prognosis and high mortality. Current severity scores such as Acute Physiology and Chronic Health Evaluation (APACHE-II) and Sequential Organ Failure Assessment (SOFA), have limited ability to help clinicians i...

Optimizing heart disease diagnosis with advanced machine learning models: a comparison of predictive performance.

BMC cardiovascular disorders
Cardiovascular disease is the leading cause of mortality globally, necessitating precise and prompt predictive instruments to enhance patient outcomes. In recent years, machine learning methodologies have demonstrated significant potential in enhanci...

Radiomics-based MRI model to predict hypoperfusion in lacunar infarction.

Magnetic resonance imaging
BACKGROUND: Approximately 20-30 % of patients with acute ischemic stroke due to lacunar infarction experience early neurological deterioration (END) within the first three days after onset, leading to disability or more severe sequelae. Hemodynamic p...

Machine Learning and Mendelian Randomization Reveal a Tumor Immune Cell Profile for Predicting Bladder Cancer Risk and Immunotherapy Outcomes.

The American journal of pathology
This study's objective was to develop predictive models for bladder cancer (BLCA) using tumor infiltrated immune cell (TIIC)-related genes. Multiple RNA expression data and scRNA-seq were downloaded from the TCGA and GEO databases. A tissue specifici...

Machine learning-based risk prediction model for neuropathic foot ulcers in patients with diabetic peripheral neuropathy.

Journal of diabetes investigation
BACKGROUND: Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes, marked by symptoms like hyperalgesia, numbness, and swelling that impair quality of life. Nerve conduction abnormalities in DPN significantly increase the ...

Using machine learning for predicting cancer-specific mortality in bladder cancer patients undergoing radical cystectomy: a SEER-based study.

BMC cancer
BACKGROUND: Accurately assessing the prognosis of bladder cancer patients after radical cystectomy has important clinical and research implications. Current models, based on traditional statistical approaches and complex variables, have limited perfo...

Development and validation of a machine learning-based nomogram for predicting prognosis in lung cancer patients with malignant pleural effusion.

Scientific reports
Malignant pleural effusion (MPE) is a common complication in patients with advanced lung cancer, significantly impacting their survival rates and quality of life. Effective tools for assessing the prognosis of these patients are urgently needed to en...

A CT-based deep learning-driven tool for automatic liver tumor detection and delineation in patients with cancer.

Cell reports. Medicine
Liver tumors, whether primary or metastatic, significantly impact the outcomes of patients with cancer. Accurate identification and quantification are crucial for effective patient management, including precise diagnosis, prognosis, and therapy evalu...