AIMC Topic: Rats, Sprague-Dawley

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Modified citrus pectin stops progression of liver fibrosis by inhibiting galectin-3 and inducing apoptosis of stellate cells.

Canadian journal of physiology and pharmacology
Modified citrus pectin (MCP) is a pH modified form of the dietary soluble citrus peel fiber known as pectin. The current study aims at testing its effect on liver fibrosis progression. Rats were injected with CCl4 (1 mL/kg, 40% v/v, i.p., twice a wee...

Simultaneous determination and pharmacokinetics of five alkaloids in rat plasma by ultra high performance liquid chromatography with tandem mass spectrometry after the oral administration of Corydalis bungeana Turcz extract.

Journal of separation science
Pharmacokinetic studies were conducted on rats for protopine, corynoline, 7'-(3',4'-dihydroxyphenyl)-N-[(4-methoxyphenyl)-ethyl]propenamide, acetylcorynoline, and 8-oxocorynoline, five main active components from Corydalis bungeana Turcz (C. bungeana...

Danhong huayu koufuye prevents deep vein thrombosis through anti-inflammation in rats.

The Journal of surgical research
BACKGROUND: Danhong huayu koufuye (DHK) has traditionally been used clinically for a long time in China. This study was to evaluate the effect of DHK in treating deep vein thrombosis (DVT) in rats and explore its possible mechanism.

A novel turning behavior control method for rat-robot through the stimulation of ventral posteromedial thalamic nucleus.

Behavioural brain research
The concept of a rat-robot was initially introduced in 2002, bringing to the field, a novel area of research using modern research into neuroscience and robotics. This paper brings to the table, a study into the method best used for navigation system...

A Novel Feature Extraction Approach Using Window Function Capturing and QPSO-SVM for Enhancing Electronic Nose Performance.

Sensors (Basel, Switzerland)
In this paper, a novel feature extraction approach which can be referred to as moving window function capturing (MWFC) has been proposed to analyze signals of an electronic nose (E-nose) used for detecting types of infectious pathogens in rat wounds....

A novel device for studying weight supported, quadrupedal overground locomotion in spinal cord injured rats.

Journal of neuroscience methods
BACKGROUND: Providing weight support facilitates locomotion in spinal cord injured animals. To control weight support, robotic systems have been developed for treadmill stepping and more recently for overground walking.

A Novel Interactive Exoskeletal Robot for Overground Locomotion Studies in Rats.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
This paper introduces a newly developed apparatus, Iron Rat, for locomotion research in rodents. Its main purpose is to allow maximal freedom of voluntary overground movement of the animal while providing forceful interaction to the hindlimbs. Advant...

Optogenetics Based Rat-Robot Control: Optical Stimulation Encodes "Stop" and "Escape" Commands.

Annals of biomedical engineering
Electric brain stimulation is frequently used in bio-robot control. However, one possible limitation of electric stimulation is the resultant wide range of influences that may lead to unexpected side-effects. Although there has been prior research do...

Integrated analysis of restraint stress in rat serum using ATR-FTIR and Raman spectroscopy with Machine learning.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
In forensic practice, accurately determining whether an individual has been subjected to prolonged restraint or assessing injuries resulting from restraint can be challenging. To address this, we explored a novel approach using attenuated total refle...

Improving Imaging Field of View of 3-D Transcranial Rat Brain Super-Resolution With Robotic Registered Compounding and Nonrigid Deformation Correction.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control
Large field-of-view (FOV) brain imaging with ultrasound has become increasingly achievable with the application of 2-D probes capable of volumetric imaging. However, even in small animals the skull presents a significant barrier and conventional plan...