AIMC Topic: Risk Factors

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Multi-omics insights of immune cells in the risk and prognosis of idiopathic membranous nephropathy.

Communications biology
Idiopathic membranous nephropathy (IMN) is the major cause of autoimmune-related nephrotic syndrome. The role immune cells play in the risk and prognosis of IMN remains elusive. We employ multi-omics data and a variety of approaches to evaluate the c...

Exposotypes in psychotic disorders.

Scientific reports
Psychiatry lags in adopting etiological approaches to diagnosis, prognosis, and outcome prediction compared to the rest of medicine. Etiological factors such as childhood trauma (CHT), substance use (SU), and socioeconomic status (SES) significantly ...

Machine Learning-Based Analysis of Lifestyle Risk Factors for Atherosclerotic Cardiovascular Disease: Retrospective Case-Control Study.

JMIR medical informatics
BACKGROUND: The risk of developing atherosclerotic cardiovascular disease (ASCVD) varies among individuals and is related to a variety of lifestyle factors in addition to the presence of chronic diseases.

Incorporation of Metabolic Dysfunction-Associated Steatotic Liver Disease in the Health Stage of Cardiovascular-Kidney-Metabolic Syndrome Improves Predictive Ability for Coronary Artery Disease in a Japanese General Population.

Journal of the American Heart Association
BACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome is a recently proposed condition encompassing metabolic dysfunction, chronic kidney disease, and cardiovascular diseases including coronary artery disease (CAD). Although concomitant metaboli...

Alzheimer's disease risk prediction using machine learning for survival analysis with a comorbidity-based approach.

Scientific reports
Alzheimer's disease (AD) presents a pressing global health challenge, demanding improved strategies for early detection and understanding its progression. In this study, we address this need by employing survival analysis techniques to predict transi...

Initiation of antifibrotic treatment in fibrosing interstitial lung disease: is the clock ticking till proven progression?

European respiratory review : an official journal of the European Respiratory Society
Several interstitial lung diseases (ILDs) with different aetiologies and pathogenic mechanisms may exhibit a progressive behaviour, similar to idiopathic pulmonary fibrosis, with comparable functional decline and early mortality. Progressive pulmonar...

Development and interpretation of a machine learning risk prediction model for post-stroke depression in a Chinese population.

Scientific reports
Current evidence for predictive models of post-stroke depression (PSD) risk based on machine learning (ML) remains limited. The aim of this study is to develop a superior predictive model based on ML algorithms for PSD in the Chinese population. We r...