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Development and Validation of a Machine Learning Algorithm After Primary Total Hip Arthroplasty: Applications to Length of Stay and Payment Models.

The Journal of arthroplasty
BACKGROUND: Value-based payment programs in orthopedics, specifically primary total hip arthroplasty (THA), present opportunities to apply forecasting machine learning techniques to adjust payment models to a specific patient or population. The objec...

Prediction of matrix metal proteinases-12 inhibitors by machine learning approaches.

Journal of biomolecular structure & dynamics
Matrix metal proteinases-12 (MMP-12) is a hot pharmaceutical target on the treatment of many human diseases. There's a crying need for designing and finding new MMP-12 inhibitors. In this work, four machine learning approaches, support vector machine...

Diagnosis of thyroid cancer using deep convolutional neural network models applied to sonographic images: a retrospective, multicohort, diagnostic study.

The Lancet. Oncology
BACKGROUND: The incidence of thyroid cancer is rising steadily because of overdiagnosis and overtreatment conferred by widespread use of sensitive imaging techniques for screening. This overall incidence growth is especially driven by increased diagn...

Radiomics-Based Intracranial Thrombus Features on CT and CTA Predict Recanalization with Intravenous Alteplase in Patients with Acute Ischemic Stroke.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Thrombus characteristics identified on non-contrast CT (NCCT) are potentially associated with recanalization with intravenous (IV) alteplase in patients with acute ischemic stroke (AIS). Our aim was to determine the best radio...

Automated detection of erythema migrans and other confounding skin lesions via deep learning.

Computers in biology and medicine
Lyme disease can lead to neurological, cardiac, and rheumatologic complications when untreated. Timely recognition of the erythema migrans rash of acute Lyme disease by patients and clinicians is crucial to early diagnosis and treatment. Our objectiv...

Quantitative ultrasound and machine learning for assessment of steatohepatitis in a rat model.

European radiology
OBJECTIVES: To develop a machine learning model based on quantitative ultrasound (QUS) parameters to improve classification of steatohepatitis with shear wave elastography in rats by using histopathology scoring as the reference standard.

Diagnosis using deep-learning artificial intelligence based on the endocytoscopic observation of the esophagus.

Esophagus : official journal of the Japan Esophageal Society
BACKGROUND AND AIMS: The endocytoscopic system (ECS) helps in virtual realization of histology and can aid in confirming histological diagnosis in vivo. We propose replacing biopsy-based histology for esophageal squamous cell carcinoma (ESCC) by usin...

A signature-based machine learning model for distinguishing bipolar disorder and borderline personality disorder.

Translational psychiatry
Mobile technologies offer new opportunities for prospective, high resolution monitoring of long-term health conditions. The opportunities seem of particular promise in psychiatry where diagnoses often rely on retrospective and subjective recall of mo...