A new, novel, rapid method to detect and direct readout of drugs in human urine has been developed using dynamic surface-enhanced Raman spectroscopy (D-SERS) with portable Raman spectrometer on gold nanorods (GNRs) and a classification algorithm call...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Dec 15, 2025
Accurate and sensitive detection of small-molecule metabolites such as uric acid, glucose, and lactic acid is critical in biomedical diagnostics and clinical applications. Traditional detection methods often face limitations such as complex procedure...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Dec 5, 2025
Early detection of uterine diseases is critically important for women's reproductive health. Here, we propose a novel and robust serum-based SERS analysis platform that integrates machine learning algorithms. This is the first application of it in th...
Bacterial sensing involves complex and variable samples that require advanced handling and analytical methods. To address these challenges, machine learning-especially deep learning-and SERS-based microfluidics have shown great promise. While previou...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Nov 15, 2025
Breast cancer is one of the most common tumors in women, and early screening can significantly reduce mortality rates. Meanwhile, accurately identifying HER2-positive and HER2-negative subtypes of breast cancer is critical for helping doctors determi...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Nov 5, 2025
In forensic practice, accurately determining whether an individual has been subjected to prolonged restraint or assessing injuries resulting from restraint can be challenging. To address this, we explored a novel approach using attenuated total refle...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Nov 5, 2025
Due to the inherent specificity and high sensitivity, biomedical detections based on Surface-Enhanced Raman Scattering (SERS) technology have garnered increasing attention. In the SERS detection process, fabricating a highly sensitive SERS substrate ...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Nov 5, 2025
Myocardial hypertrophy and heart failure are leading causes of mortality in cardiovascular diseases, yet current diagnostic techniques lack the resolution to monitor molecular changes effectively. In this study, we employed confocal Raman spectroscop...
Osteosarcoma (OS) calls for early diagnosis to significantly improve patient survival rates. Exosomes hold significant potential as noninvasive biomarkers for the early diagnosis of cancer. Here, we design a microfluidic device to purify and analyze ...
International journal of food microbiology
Sep 2, 2025
Botryosphaeria dothidea infection has become a major factor affecting the quality of postharvest fruits, so detection of B. dothidea infection is very important to control the spread of infection and ensure food safety. In this study, we built a moni...
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