AIMC Topic: Aged

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Lipidomic analysis coupled with machine learning identifies unique urinary lipid signatures in patients with interstitial cystitis/bladder pain syndrome.

World journal of urology
PURPOSE: To identify biomarkers for diagnosis and classification of interstitial cystitis/bladder pain syndrome (IC/BPS) by urinary lipidomics coupled with machine learning.

Daily Automated Prediction of Delirium Risk in Hospitalized Patients: Model Development and Validation.

JMIR medical informatics
BACKGROUND: Delirium is common in hospitalized patients and is correlated with increased morbidity and mortality. Despite this, delirium is underdiagnosed, and many institutions do not have sufficient resources to consistently apply effective screeni...

Decoding Recurrence in Early-Stage and Locoregionally Advanced Non-Small Cell Lung Cancer: Insights From Electronic Health Records and Natural Language Processing.

JCO clinical cancer informatics
PURPOSE: Recurrences after curative resection in early-stage and locoregionally advanced non-small cell lung cancer (NSCLC) are common, necessitating a nuanced understanding of associated risk factors. This study aimed to establish a natural language...

DWI of the rectum with deep learning reconstruction: comparison of PROPELLER, reduced FOV, and conventional DWI.

Abdominal radiology (New York)
PURPOSE: To compare the image quality and diagnostic performance of periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER), reduced field-of-view (rFOV), and conventional diffusion-weighted imaging (cDWI) combined wi...

Machine learning based radiomic models outperform clinical biomarkers in predicting outcomes after immunotherapy for hepatocellular carcinoma.

Journal of hepatology
BACKGROUND & AIMS: Atezolizumab plus bevacizumab (A/B) is a first-line therapy for unresectable hepatocellular carcinoma (HCC). Only a small proportion of patients respond to treatment. This study integrated radiomic and clinical data derived from ro...

Combined peritumoral radiomics and clinical features predict 12-month progression free survival in glioblastoma.

Journal of neuro-oncology
PURPOSE: Analyzing post-treatment MRIs from glioblastoma patients can be challenging due to similar radiological presentations of disease progression and treatment effects. Identifying radiomics features (RFs) revealing progressive glioblastoma can c...

Fully Automated Online Adaptive Radiation Therapy Decision-Making for Cervical Cancer Using Artificial Intelligence.

International journal of radiation oncology, biology, physics
BACKGROUND: Interfraction variations during radiation therapy pose a challenge for patients with cervical cancer, highlighting the benefits of online adaptive radiation therapy (oART). However, adaptation decisions rely on subjective image reviews by...

Transcriptomic analyses of human brains with Alzheimer's disease identified dysregulated epilepsy-causing genes.

Epilepsy & behavior : E&B
BACKGROUND & OBJECTIVE: Alzheimer's Disease (AD) patients at multiple stages of disease progression have a high prevalence of seizures. However, whether AD and epilepsy share pathophysiological changes remains poorly defined. In this study, we levera...

Performance and hypothetical clinical impact of an mNGS-based machine learning model for antimicrobial susceptibility prediction of five ESKAPEE bacteria.

Microbiology spectrum
UNLABELLED: Antimicrobial resistance is an escalating global health crisis, underscoring the urgent need for timely and targeted therapies to ensure effective clinical treatment. We developed a machine learning model based on metagenomic next-generat...

Assessing the association of multi-environmental chemical exposures on metabolic syndrome: A machine learning approach.

Environment international
Metabolic syndrome (MetS) is a major global public health concern due to its rising prevalence and association with increased risks of cardiovascular disease and type 2 diabetes. Emerging evidence suggests that environmental chemical exposures may pl...