OBJECTIVES: To develop a cascaded machine learning model based on MRI radiomics features from cartilage and subchondral bone to predict the incidence and progression of knee osteoarthritis (KOA), thereby addressing the need for early intervention in ...
OBJECTIVE: Freezing of gait (FOG) is a common gait disorder in the advanced stages of Parkinson's disease (PD), closely associated with impaired balance and executive function. This study aimed to investigate specific changes in brain glucose metabol...
PURPOSE: The decline in activities of daily living (ADL) among older persons is a significant public health concern. Sarcopenia is a major risk factor for ADL disability. This study aimed to develop and validate an interpretable machine learning (IML...
Amyotrophic lateral sclerosis (ALS) is a rare and fatal neurodegenerative disease with a median survival of only 2 to 4 years from diagnosis. Improved tools are needed to shorten diagnostic delays and improve prognostication to benefit clinical care....
Acute ischemic stroke is a major global health challenge, leading to long-term disability or death without timely intervention. Among neuroimaging modalities, spatio-temporal (4D) computed tomography perfusion (CTP) is widely used to assess cerebral ...
Depression, which is increasingly prevalent among older adults, has traditionally been diagnosed through symptom-based questionnaires. However, emerging evidence suggests that retinal changes could serve as objective biomarkers for depression. In thi...
BACKGROUND: Coronary artery disease (CAD) is one of the biggest causes of mortality worldwide. Risk stratification for early detection is essential for the primary prevention of CAD. QRISK3 is known to overestimate future CAD risk in some populations...
PURPOSE: This study evaluated the dynamic changes in the tumor microenvironment (TME) in patients with non-small cell lung cancer (NSCLC) and acquired resistance to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) using an ar...
OBJECTIVE: To utilize machine learning techniques to screen contrast-enhanced ultrasound (CEUS) parameters and clinical characteristics, aiming to differentiate diabetic nephropathy (DN) from non-diabetic renal disease (NDRD) in patients with diabeti...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.