AIMC Topic: Atherosclerosis

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Association Between Genotypes and Risk of Cardiovascular Disease in MESA (Multi-Ethnic Study of Atherosclerosis).

Journal of the American Heart Association
BACKGROUND: genetic variants confer an increased risk for kidney disease. Their associations with cardiovascular disease (CVD) are less certain. We aimed to compare the prevalence of subclinical CVD and incidence of atherosclerotic CVD and heart fai...

Oleanolic acid protects against pathogenesis of atherosclerosis, possibly via FXR-mediated angiotensin (Ang)-(1-7) upregulation.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Atherosclerosis, the leading cause of cardiovascular diseases in the world, is a chronic inflammatory disorder characterized by the dysfunction of arteries. Oleanolic acid (OA) is a bioactive nature product which exists in various plants and herbs. P...

Premature atherosclerosis after treatment for acute lymphoblastic leukemia in childhood.

Annals of agricultural and environmental medicine : AAEM
INTRODUCTION: Late cardiovascular complications are the leading causes of morbidity and mortality in patients treated for common malignancies of childhood. Late cardiotoxicity include increased development of atherosclerosis and atherosclerosis - rel...

Icariin improves eNOS/NO pathway to prohibit the atherogenesis of apolipoprotein E-null mice.

Canadian journal of physiology and pharmacology
Impaired endothelial nitric oxide synthase (eNOS)/nitric oxide (NO) pathway induces atherogenesis. The present study examined whether icariin improves the eNOS/NO pathway to prohibit the atherogenesis of apolipoprotein E-null (ApoE) mice. In vitro, p...

Carotid Intima-Media Thickness and Visit-to-Visit HbA1c Variability Predict Progression of Chronic Kidney Disease in Type 2 Diabetic Patients with Preserved Kidney Function.

Journal of diabetes research
. Subclinical atherosclerosis and long-term glycemic variability have been reported to predict incident chronic kidney disease (CKD) in the general population. However, these associations have not been investigated in patients with type 2 diabetes wi...

Deficient serum 25-hydroxyvitamin D is associated with an atherogenic lipid profile: The Very Large Database of Lipids (VLDL-3) study.

Journal of clinical lipidology
BACKGROUND: Cross-sectional studies have found an association between deficiencies in serum vitamin D, as measured by 25-hydroxyvitamin D (25[OH]D), and an atherogenic lipid profile. These studies have focused on a limited panel of lipid values inclu...

PET imaging of atherosclerosis: artificial intelligence applications and recent advancements.

Nuclear medicine communications
PET imaging has become a valuable tool for assessing atherosclerosis by targeting key processes such as inflammation and microcalcification. Among available tracers, 18F-sodium fluoride has demonstrated superior performance compared to 18F-fluorodeox...

The role of mitochondrial dysfunction in the pathogenesis of atherosclerosis: A new exploration from bioinformatics analysis.

Medicine
Atherosclerosis (AS) is a complex cardiovascular disease associated with mitochondrial dysfunction (MD), which contributes to plaque formation and instability. This study explores the relationship and shared risk factors between the pathogenesis of A...