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Atherosclerosis

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Association of Cardiovascular Mortality and Deep Learning-Funduscopic Atherosclerosis Score derived from Retinal Fundus Images.

American journal of ophthalmology
PURPOSE: The prediction of atherosclerosis using retinal fundus images and deep learning has not been shown possible. The purpose of this study was to develop a deep learning model which predicted atherosclerosis by using retinal fundus images and to...

Oral microbiome-systemic link studies: perspectives on current limitations and future artificial intelligence-based approaches.

Critical reviews in microbiology
In the past decade, there has been a tremendous increase in studies on the link between oral microbiome and systemic diseases. However, variations in study design and confounding variables across studies often lead to inconsistent observations. In th...

Label-Free Tomographic Imaging of Lipid Droplets in Foam Cells for Machine-Learning-Assisted Therapeutic Evaluation of Targeted Nanodrugs.

ACS nano
Lipid droplet (LD) accumulation, a key feature of foam cells, constitutes an attractive target for therapeutic intervention in atherosclerosis. However, despite advances in cellular imaging techniques, current noninvasive and quantitative methods hav...

Computer-assisted prediction of atherosclerotic intimal thickness based on weight of adrenal gland, interleukin-6 concentration, and neural networks.

The Journal of international medical research
OBJECTIVE: Atherosclerosis (AS) is the main pathological basis of ischemic cardio-cerebrovascular diseases, and the intimal thickness (IT) of large arteries is regarded as a powerful evaluation indicator for AS. We established an effective neural net...

Automatic identification of atherosclerosis subjects in a heterogeneous MR brain imaging data set.

Magnetic resonance imaging
Carotid-artery atherosclerosis (CA) contributes significantly to overall morbidity and mortality in ischemic stroke. We propose a machine learning technique to automatically identify subjects with CA from a heterogeneous cohort of magnetic resonance ...

Generalized multifactor dimensionality reduction approaches to identification of genetic interactions underlying ordinal traits.

Genetic epidemiology
The manifestation of complex traits is influenced by gene-gene and gene-environment interactions, and the identification of multifactor interactions is an important but challenging undertaking for genetic studies. Many complex phenotypes such as dise...

Rheumatoid Arthritis: Atherosclerosis Imaging and Cardiovascular Risk Assessment Using Machine and Deep Learning-Based Tissue Characterization.

Current atherosclerosis reports
PURPOSE OF THE REVIEW: Rheumatoid arthritis (RA) is a chronic, autoimmune disease which may result in a higher risk of cardiovascular (CV) events and stroke. Tissue characterization and risk stratification of patients with rheumatoid arthritis are a ...

Expression of socially sensitive genes: The multi-ethnic study of atherosclerosis.

PloS one
BACKGROUND: Gene expression may be an important biological mediator in associations between social factors and health. However, previous studies were limited by small sample sizes and use of differing cell types with heterogeneous expression patterns...