RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
Dec 1, 2025
Ovarian cancer remains a significant cause of mortality among women, largely due to challenges in early detection. Current screening strategies, including transvaginal ultrasound and CA125 testing, have limited sensitivity and specificity, particular...
INTRODUCTION: A new perspective on cancer metabolism suggests that it varies by context and is diverse. Cancer metabolism reprogramming can create a heterogeneous microenvironment that affects immune cell infiltration and function, complicating the s...
Acute myeloid leukemia (AML) is characterized by a low 5-year survival rate. Despite having many clinical metrics to assess patient prognosis, there remain opportunities to improve risk stratification. We hypothesized that an underexplored resource t...
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Nov 15, 2025
We pioneer a multimodal framework integrating single-cell RNA sequencing (scRNA-seq), radiomics, and deep learning to decipher dendritic cell (DC)-mediated mechanisms underlying anti-PD-1 response in non-small cell lung cancer (NSCLC). Single-cell RN...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Nov 15, 2025
Breast cancer is one of the most common tumors in women, and early screening can significantly reduce mortality rates. Meanwhile, accurately identifying HER2-positive and HER2-negative subtypes of breast cancer is critical for helping doctors determi...
Clinical cancer research : an official journal of the American Association for Cancer Research
Nov 14, 2025
PURPOSE: Treatment with immune checkpoint inhibitors (ICI) in advanced melanoma can result in durable responses, yet an algorithm to decide which patients can safely discontinue ICI is still lacking.
International journal of radiation oncology, biology, physics
Nov 1, 2025
PURPOSE: The study aimed to develop machine learning (ML) models for pretherapy prediction of absorbed doses (ADs) in kidneys and tumoral lesions for patients with metastatic castration-resistant prostate cancer (mCRPC) undergoing [Lu]Lu-PSMA-617 (Lu...
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Nov 1, 2025
Pancreatic cancer (PC) remains one of the most lethal malignancies, primarily due to its poor prognosis and late diagnosis. Biomarkers are essential in enhancing diagnostic accuracy, prognostic assessments, and therapeutic strategies, thereby address...
Osteosarcoma (OS) calls for early diagnosis to significantly improve patient survival rates. Exosomes hold significant potential as noninvasive biomarkers for the early diagnosis of cancer. Here, we design a microfluidic device to purify and analyze ...
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Oct 31, 2025
Protein arginine methylation was a common post-translational modification, playing a key role in many biological processes and disease. But the regulatory mechanisms of protein arginine methyltransferases (PRMTs) in cancer were not well understood. T...
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