Archives of gynecology and obstetrics
Jan 20, 2026
INTRODUCTION: We aimed to develop a machine learning model for first-trimester prediction of gestational diabetes mellitus (GDM) in twin pregnancies using a prospective international, multi-center cohort and identify useful predictive markers. METHOD...
BACKGROUND: Staphylococcus aureus (S. aureus) pneumonia constitutes a lethal respiratory infection with persistently high clinical mortality. Although programmed cell death (PCD) pathways are implicated in diverse disease processes, their mechanistic...
BACKGROUND: Abdominal aortic aneurysm (AAA) refers to a lasting enlargement of the abdominal aorta. Senescence, a major risk factor of AAA, demonstrate positive connection with both the formation and rupture of aneurysms. Therefore, investigating the...
Objective.Large vessel occlusion (LVO) stroke presents a major challenge in clinical practice due to the potential for poor outcomes with delayed treatment. Treatment for LVO involves highly specialized care, in particular endovascular thrombectomy, ...
BACKGROUND: The World Health Organization encourages the development of novel diagnostic tools based on 'non-sputum' samples to meet global goals for tuberculosis (TB) control. We aimed to develop a machine learning-driven model for TB diagnosis, usi...
Mammalian genome : official journal of the International Mammalian Genome Society
Jan 16, 2026
Gestational diabetes mellitus (GDM) is characterized by glucose intolerance during pregnancy, resulting from insulin resistance, and is associated with increased maternal and neonatal risks. Inflammasomes play a critical role in GDM pathophysiology b...
OBJECTIVE: This study aimed to identify diagnostic biomarkers for keloid and explore potential therapeutic agents from traditional Chinese medicine (TCM) by integrating network pharmacology approaches. Specifically, we sought to uncover key molecular...
Signal transduction and targeted therapy
Jan 14, 2026
Acute pancreatitis is a complex inflammatory condition characterized by sudden onset and rapid progression, with severe cases often associated with high mortality. In recent years, the global incidence of acute pancreatitis has been increasing, with ...
UNLABELLED: Early identification of children at high risk for moderate-to-severe obstructive sleep apnea (OSA) is crucial for timely intervention, yet is often hindered by limited access to polysomnography (PSG). We aimed to develop an interpretable ...
Acute myocardial infarction (AMI) remains a leading cause of global cardiovascular morbidity and mortality. Limitations in current diagnostic methods hinder early detection and intervention, creating an urgent need for novel early diagnostic biomarke...
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