AIMC Topic: Biomarkers

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CSF YKL-40 and pTau181 are related to different cerebral morphometric patterns in early AD.

Neurobiology of aging
Cerebrospinal fluid (CSF) concentrations of YKL-40 that serve as biomarker of neuroinflammation are known to be altered along the clinico-biological continuum of Alzheimer's disease (AD). The specific structural cerebral correlates of CSF YKL-40 were...

Characterization of the abnormal lipid profile in Chinese patients with psoriasis.

International journal of clinical and experimental pathology
Psoriasis is a chronic inflammatory skin disease that has been associated with abnormal lipid metabolism. To characterize the lipid profile in Chinese, 86 patients with psoriasis and 84 healthy control subjects were assessed. Compared with healthy co...

Influence of protein kinase C (PKC) on the prognosis of diabetic nephropathy patients.

International journal of clinical and experimental pathology
AIMS: To investigate the association between protein kinase C (PKC) and the prognosis of patients with diabetic nephropathy (DN).

Label-free blood serum detection by using surface-enhanced Raman spectroscopy and support vector machine for the preoperative diagnosis of parotid gland tumors.

BMC cancer
BACKGROUND: It is difficult for the parotid gland neoplasms to make an accurate preoperative diagnosis due to the restriction of biopsy in the parotid gland neoplasms. The aim of this study is to apply the surface-enhanced Raman spectroscopy (SERS) m...

Automated Classification of Circulating Tumor Cells and the Impact of Interobsever Variability on Classifier Training and Performance.

Journal of immunology research
Application of personalized medicine requires integration of different data to determine each patient's unique clinical constitution. The automated analysis of medical data is a growing field where different machine learning techniques are used to mi...

Predictive Value of Neutrophil Gelatinase-Associated Lipocalin for Contrast-Induced Acute Kidney Injury After Cardiac Catheterization: A Meta-analysis.

The Canadian journal of cardiology
BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) accumulates in cortical tubules in acute kidney injury (AKI) patients, with its levels associated with serum creatinine. However, the predictive value of NGAL level for contrast-induced ac...

Classifying Stress From Heart Rate Variability Using Salivary Biomarkers as Reference.

IEEE transactions on neural networks and learning systems
An accurate and noninvasive stress assessment from human physiology is a strenuous task. In this paper, a pattern recognition system to learn complex correlates between heart rate variability (HRV) features and salivary stress biomarkers is proposed....

Muscle damage and immune responses to prolonged exercise in environmental extreme conditions.

The Journal of sports medicine and physical fitness
BACKGROUND: This study aimed to investigate the effect of prolonged exercise with and without a thermal clamp on leukocyte cell, stress hormones, cytokine and muscle damage responses.

Fuzzy Modeling to Predict Severely Depressed Left Ventricular Ejection Fraction following Admission to the Intensive Care Unit Using Clinical Physiology.

TheScientificWorldJournal
Left ventricular ejection fraction (LVEF) constitutes an important physiological parameter for the assessment of cardiac function, particularly in the settings of coronary artery disease and heart failure. This study explores the use of routinely and...