BACKGROUND: The molecular and genetic mechanisms underlying vascular calcification remain unclear. This study aimed to determine the differences in calcification marker-related gene expression in macrophages.
Neural networks : the official journal of the International Neural Network Society
Jul 1, 2025
In this study, we propose a subspace-enhanced hypergraph neural network (seHGNN) for classifying anxiety disorders (AD), which are prevalent mental illnesses that affect a significant portion of the global population. Our seHGNN model utilizes a lear...
BACKGROUND: Early diagnosis, close follow-up and timely delivery constitute the main elements for appropriate detection and management of Fetal Growth Disorders (FGD). We hypothesized that fetoplacental FGD-associated alterations can be detected in c...
Airborne microplastics (MPs) pose significant respiratory and systemic health risks upon inhalation; however, current assessment methods remain inadequate. This study integrates breathomics and transcriptomics to establish a non-invasive approach for...
BACKGROUND: Fibrosis is a common complication in Crohn's disease (CD), often leading to intestinal strictures. This study aims to explore the transcriptomic signature of fibrostenotic ileal CD for a comprehensive characterization of biological and ce...
Journal of the American Society for Mass Spectrometry
Jun 4, 2025
Early recognition of septic shock is crucial for improving clinical management and patient outcomes, especially in the emergency department (ED). This study conducted serum metabolomic profiling on ED patients diagnosed with septic shock (n = 32) and...
Osteoarthritis is a multifactorial condition marked by the gradual deterioration of joint cartilage, synovial inflammation, alterations in the subchondral bone and changes in the surrounding soft tissues. Clinical assessments and patient-reported out...
Coronary artery disease (CAD) commonly occurs and elevates the risk of cardiovascular events and mortality in chronic kidney disease (CKD) patients. The underlying pathogenesis of CKD-related CAD is believed to be closely linked to inflammatory respo...
PURPOSE: Age-related macular degeneration (AMD) remains the leading cause of blindness in developed countries. There are many different intravitreal anti-vascular endothelial growth factor (VEGF) drugs available for the treatment of neovascular AMD (...
BACKGROUND: Machine-learning models directly predicting iron biomarkers after blood donation could help to manage donation-associated iron deficiency and avoid low haemoglobin deferrals. No such models have been externally validated internationally. ...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.