BACKGROUND: Oxidative stress was one of key factors driving the septic development by the uncontrolled accumulation of free radicals, thus oxidative stress-related biomarkers provide a novel diagnostic option. This study focused on screening oxidativ...
OBJECTIVE: Endometriosis is a prevalent gynecological disease characterized by the ectopic growth of functional endometrial tissue outside the uterine cavity, affecting millions of women worldwide. Currently, the definitive diagnosis relies on invasi...
BACKGROUND: Major depressive disorder (MDD) exhibits a multifactorial etiopathogenesis, yet current diagnosis still relies on clinician-rated symptom scales and phenomenological interviews, lacking validated biomarkers.
Circulation journal : official journal of the Japanese Circulation Society
Jun 17, 2025
BACKGROUND: B-type natriuretic peptide (BNP) and N-terminal pro-BNP (NT-pro-BNP) are key biomarkers used for heart failure (HF) management. Although traditional auscultation lacks objective evaluation, the SSS01-series phonocardiogram enables rapid r...
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Jun 17, 2025
OBJECTIVES: Avian influenza such as H7N9 is currently a major global public health risk, and at present, there is a lack of relevant diagnostic and treatment markers.
The journal of physical chemistry letters
Jun 15, 2025
Accurate and early detection of C-peptide, a stable biomarker indicative of diabetes, is crucial for disease diagnosis, treatment, and prevention. This study explores a novel detection methodology using solid-state nanopore technology coupled with ma...
Current opinion in nephrology and hypertension
Jun 12, 2025
PURPOSE OF REVIEW: The purpose of this review is to describe recent and important updates in acute kidney injury (AKI) phenotyping that help us to move beyond the clinical syndrome of AKI.
Metabolomics, the study of small molecules within biological systems, offers insights into metabolic processes and, consequently, holds great promise for advancing health outcomes. Biomarker discovery in metabolomics represents a significant challeng...
Coronary microvascular disease (CMD), particularly prevalent among women, is associated with increased morbidity and mortality, making clinical screening vital for effective management. However, limited publicly available screening-level data hinders...
Recent advances in experimental methods have enabled researchers to collect data on thousands of analytes simultaneously. This has led to correlational studies that associated molecular measurements with diseases such as Alzheimer's, Liver, and Gastr...
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