AIMC Topic: Cell Movement
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Deep learning guided image-based droplet sorting for on-demand selection and analysis of single cells and 3D cell cultures.
Lab on a chip
Mar 3, 2020
Uncovering the heterogeneity of cellular populations and multicellular constructs is a long-standing goal in fields ranging from antimicrobial resistance to cancer research. Emerging technology platforms such as droplet microfluidics hold the promise...
DriverML: a machine learning algorithm for identifying driver genes in cancer sequencing studies.
Nucleic acids research
May 7, 2019
Although rapid progress has been made in computational approaches for prioritizing cancer driver genes, research is far from achieving the ultimate goal of discovering a complete catalog of genes truly associated with cancer. Driver gene lists predic...
[Effects of long non-coding RNA RP1-90L14.1 on the biological behaviors of cancer prostate LNCaP cells and its regulating mechanisms].
Zhonghua nan ke xue = National journal of andrology
Mar 1, 2019
OBJECTIVE: To investigate the effects of long non-coding RNA RP1-90L14.1 on the proliferation, migration and invasion of prostate cancer LNCaP cells and the expressions of GRIN2A and BACE2.
Morphology-based prediction of cancer cell migration using an artificial neural network and a random decision forest.
Integrative biology : quantitative biosciences from nano to macro
Dec 19, 2018
Metastasis is the cause of death in most patients of breast cancer and other solid malignancies. Identification of cancer cells with highly migratory capability to metastasize relies on markers for epithelial-to-mesenchymal transition (EMT), a proces...
Humans
Reproducibility of Results
Breast Neoplasms
Animals
Neoplasms
Neural Networks, Computer
Algorithms
Decision Support Techniques
Female
Neoplasm Metastasis
Mice
Lab-On-A-Chip Devices
Cell Movement
Epithelial-Mesenchymal Transition
Models, Biological
Deep Learning
Cell Line, Tumor
Single-Cell Analysis
[Effect of Brucea javanica oil emulsion on proliferation, migration and autophagy of non-small cell lung cancer A549 cells and the underlying mechanisms].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
Nov 28, 2018
To investigate the effect of Brucea javanica oil emulsion on proliferation, migration and autophagy of non-small cell lung cancer A549 cells.
Methods: First, A549 cells were divided into a control group and a low, medium or high dose of Brucea javan...
Potential Anticancer Activity of the Parasol Mushroom, Macrolepiota procera (Agaricomycetes), against the A549 Human Lung Cancer Cell Line.
International journal of medicinal mushrooms
Jan 1, 2018
Mushrooms comprise an unlimited source of active compounds that have beneficial health effects without known negative side effects and can potentially be used as important therapeutic products against cancer, which is the leading cause of death world...
[Apple polyphenol inhibited the proliferation and migration of breast cancer cell MDA-MB-231 mediated by UHRF1].
Wei sheng yan jiu = Journal of hygiene research
Nov 1, 2017
OBJECTIVE: To investigate the effects of apple polyphenol on cell proliferation and migration of breast cancer cell line MDA-MB-231, and explore the potential mechanism.
Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancer.
Oncotarget
Apr 18, 2017
We demonstrate that model-based unsupervised learning can uniquely discriminate single-cell subpopulations by their gene expression distributions, which in turn allow us to identify specific genes for focused functional studies. This method was appli...
Metformin
Gene Knockdown Techniques
cdc42 GTP-Binding Protein
Cluster Analysis
Unsupervised Machine Learning
AMP-Activated Protein Kinases
Female
Breast Neoplasms
Gene Expression Profiling
Cell Line, Tumor
Computational Biology
Gene Expression Regulation, Neoplastic
Signal Transduction
Cell Movement
Humans
Effect of doxycycline on transforming growth factor-beta-1-induced matrix metalloproteinase 2 expression, migration, and collagen contraction in nasal polyp-derived fibroblasts.
American journal of rhinology & allergy
Nov 1, 2016
PURPOSE: It is well known that doxycycline has antibacterial and anti-inflammatory effects. In this study, we aimed to investigate the effects of doxycycline on the transforming growth factor (TGF) beta 1-induced matrix metalloproteinase (MMP) 2 expr...
Controlled regular locomotion of algae cell microrobots.
Biomedical microdevices
Jun 1, 2016
Algae cells can be considered as microrobots from the perspective of engineering. These organisms not only have a strong reproductive ability but can also sense the environment, harvest energy from the surroundings, and swim very efficiently, accommo...
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