AIMC Topic: Female
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Menopausal hormone therapy and the female brain: Leveraging neuroimaging and prescription registry data from the UK Biobank cohort.
eLife
May 29, 2025
BACKGROUND: Menopausal hormone therapy (MHT) is generally thought to be neuroprotective, yet results have been inconsistent. Here, we present a comprehensive study of MHT use and brain characteristics in females from the UK Biobank.
Exploring the medical ethical limitations of GPT-4 in clinical decision-making scenarios: a pilot survey.
Frontiers in public health
May 29, 2025
BACKGROUND: This study aims to conduct an examination of GPT-4's tendencies when confronted with ethical dilemmas, as well as to ascertain their ethical limitations within clinical decision-makings.
Development of a machine learning-based predictive nomogram for screening children with juvenile idiopathic arthritis: a pseudo-longitudinal study of 223,195 children in the United States.
Frontiers in public health
May 29, 2025
BACKGROUND: Juvenile idiopathic arthritis (JIA) is a prevalent chronic rheumatological condition in children, with reported prevalence ranging from 12. 8 to 45 per 100,000 and incidence rates from 7.8 to 8.3 per 100,000 person-years. The diagnosis of...
Improving cancer detection through computer-aided diagnosis: A comprehensive analysis of nonlinear and texture features in breast thermograms.
PloS one
May 29, 2025
Breast cancer is a significant health issue for women, characterized by its high rates of mortality and sickness. However, its early detection is crucial for improving patient outcomes. Thermography, which measures temperature variations between heal...
Inflammatory biomarkers as predictors for unlocking antidepressant efficacy: Assessing predictive value and risk stratification in major depressive disorder in a prospective longitudinal study.
Journal of affective disorders
May 28, 2025
BACKGROUND: Major depressive disorder (MDD) is characterized by significant heterogeneity in treatment response, with inflammation hypothesized to play a role in its pathophysiology. Peripheral inflammatory biomarkers, such as the neutrophil-to-lymph...
OSAM-NET: A multi-feature fusion model for measuring fetal head flexion during labor with transformer multi-head self-attention.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
May 28, 2025
Fetal head flexion is essential during labor. The current assessment presents technical challenges for unskilled ultrasound operators. Therefore, the study aimed to propose an occiput-spine angle measurement network (OSAM-NET) to improve the accuracy...
An Artificial Intelligence Olfactory-Based Diagnostic Model for Parkinson's Disease Using Volatile Organic Compounds from Ear Canal Secretions.
Analytical chemistry
May 28, 2025
Parkinson's Disease (PD), a frequently diagnosed neurodegenerative condition, poses a major global challenge. Early diagnosis and intervention are crucial for PD treatment. This study proposes a diagnostic model for PD that analyzes volatile organic ...
Contrastive functional connectivity defines neurophysiology-informed symptom dimensions in major depression.
Cell reports. Medicine
May 28, 2025
Major depressive disorder (MDD) is highly heterogeneous, posing challenges for effective treatment due to complex interactions between clinical symptoms and neurobiological features. To address this, we apply contrastive principal-component analysis ...
An integrated analytical approach for biomarker discovery in esophageal cancer: Combining trace element and oxidative stress profiling with machine learning.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
May 28, 2025
BACKGROUND: Early detection of esophageal squamous cell carcinoma (ESCC) significantly improves survival rates, yet reliable biochemical biomarkers for early diagnosis remain limited. The aim of this study is to identify potential early diagnostic bi...
Deep learning for predicting invasive recurrence of ductal carcinoma in situ: leveraging histopathology images and clinical features.
EBioMedicine
May 28, 2025
BACKGROUND: Ductal Carcinoma In Situ (DCIS) can progress to ipsilateral invasive breast cancer (IBC) but over 75% of DCIS lesions do not progress if untreated. Currently, DCIS that might progress to IBC cannot reliably be identified. Therefore, most ...
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