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Prospective quality control in chest radiography based on the reconstructed 3D human body.

Physics in medicine and biology
Chest radiography requires effective quality control (QC) to reduce high retake rates. However, existing QC measures are all retrospective and implemented after exposure, often necessitating retakes when image quality fails to meet standards and ther...

Dissecting Exosomal-Tumoral-Vascular Interactions of Single Tumor Cells and Clusters Using a Tumoral-Transendothelial Migration Chip.

ACS nano
The complex interplay between tumor cells and clusters with endothelial tissues during metastasis, in particular with regard to the exosomes in mediating intercellular communication, is still not well understood. Here, we develop a tumoral-transendot...

Serum-Based Detection of Pancreatic and Ovarian Cancer via a Nanoparticle-Enhanced Fluorescence Array and Machine Learning.

Analytical chemistry
: Early detection of oncological diseases such as pancreatic ductal adenocarcinoma (PDAC) and ovarian cancer (OV) is pivotal for successful treatment but remains a significant challenge due to the lack of sensitive and specific diagnostic tests. Fluo...

Novel composite health assessment risk model for older allogeneic transplant recipients: BMT-CTN 1704.

Blood advances
Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for older adults with hematologic malignancies. Concerns on nonrelapse mortality (NRM) in older adults limit allo-HCT utilization. We executed a prospective, observation...

Prediction of Adolescent Suicide Attempt by Integrating Clinical, Neurocognitive and Geocoded Neighborhood Environment Data.

Schizophrenia bulletin
BACKGROUND AND HYPOTHESIS: Suicide attempt is a complex behavior influenced by a combination of factors including clinical, neurocognitive, and environmental. We aimed to leverage multimodal data collected during pre/early adolescence in research set...

A multi-omics machine learning classifier for outgrowth of cow's milk allergy in children.

Molecular omics
Cow's milk protein allergy (CMA) is one of the most common food allergies in children worldwide. However, it is still not well understood why certain children outgrow their CMA and others do not. While there is increasing evidence for a link of CMA w...

Prediction of tissue and clinical thrombectomy outcome in acute ischaemic stroke using deep learning.

Brain : a journal of neurology
The advent of endovascular thrombectomy has significantly improved outcomes for stroke patients with intracranial large vessel occlusion, yet individual benefits can vary widely. As demand for thrombectomy rises and geographical disparities in stroke...

Artificial intelligence models using F-wave responses predict amyotrophic lateral sclerosis.

Brain : a journal of neurology
Nerve conduction F-wave studies contain crucial information about subclinical motor dysfunction that can be used to diagnose patients with amyotrophic lateral sclerosis (ALS). However, F-wave responses are highly variable in morphology, making wavefo...

Modeling the Determinants of Subjective Well-Being in Schizophrenia.

Schizophrenia bulletin
BACKGROUND: The ultimate goal of successful schizophrenia treatment is not just to alleviate psychotic symptoms, but also to reduce distress and achieve subjective well-being (SWB). We aimed to identify the determinants of SWB and their interrelation...

Protocol for a multicenter randomized controlled trial to assess the usefulness of computer-aided detection systems for colonoscopy in colorectal cancer screening in the Asia-Pacific region (project CAD/NCCH2217).

Japanese journal of clinical oncology
Ensuring the high quality of colonoscopies in colorectal cancer (CRC) screening is essential to reducing CRC. Recently, computer-aided detection systems (CADe) that use artificial intelligence have attracted much attention as potentially useful tools...