Telomeres, the nucleoprotein structures at the ends of chromosomes, have emerged as critical regulators of cellular aging and key contributors to the pathogenesis of age-related diseases. This comprehensive review examines the evolution of telomere b...
The increasing zoonotic potential of highly pathogenic avian influenza (HPAI) H5N1 poses a growing threat to global public health. This review examines the molecular and evolutionary mechanisms facilitating H5N1 adaptation in mammalian hosts, focusin...
Cellular heterogeneity of epithelial cells and fibroblasts is critical in esophageal squamous cell carcinoma development (ESCC). Identifying dysregulated subtype-specific genes in these cells is essential for early diagnosis and treatment. In this st...
Turkish journal of haematology : official journal of Turkish Society of Haematology
Aug 12, 2025
Patient blood management (PBM) is an evidence-based, multidisciplinary approach aimed at optimizing the care of patients who might require transfusion. While PBM has been widely adopted in adult practice, its application in pediatric settings remains...
BACKGROUND: Recently, robotic arms have been incorporated into the implantation of electrodes for deep brain stimulation (DBS).This study aimed to determine the accuracy of brain electrode placement, initial clinical efficacy, and safety profile of t...
BACKGROUND: We aimed to quantify hepatic vessel volumes across chronic liver disease stages and healthy controls using deep learning-based magnetic resonance imaging (MRI) analysis, and assess correlations with biomarkers for liver (dys)function and ...
Metabolomics : Official journal of the Metabolomic Society
Aug 12, 2025
INTRODUCTION: The degree of antimicrobial resistance demonstrated by carbapenemase-producing Enterobacterales (CPE) represents a growing public health challenge. Conventional methods for detecting CPE involve culture-based techniques with lengthy inc...
Interstitial lung disease (ILD) is a common and serious organ manifestation in patients with connective tissue disease (CTD), but it is uncertain whether there is a difference in ILD between symptomatic and asymptomatic patients. Therefore, we conduc...
Cardiomyopathies pose a significant risk of morbidity and mortality worldwide, with dilated cardiomyopathy (DCM) recognized as the leading cause of pediatric heart transplantation. Understanding the unique presentation of DCM in the pediatric populat...
OBJECTIVES: The aim of this study was to evaluate GPT-4o's multimodal reasoning ability to review panoramic radiograph (PR) and verify its radiologic findings, while exploring the role of prompt engineering in enhancing its performance.
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