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A simple LC-MS/MS method for determination of deferasirox in human plasma: Troubleshooting of interference from ferric ion in method development and its application.

Journal of pharmaceutical and biomedical analysis
As an orally active iron chelator, deferasirox forms its ion complexes in the prepared plasma samples and LC-MS mobile phase where ferric ion exists, and then comparing with the nominal concentration level, a lower detected concentration level of def...
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Variants in GNPTAB, GNPTG and NAGPA genes are associated with stutterers.

Gene
Non-syndromic stuttering is a neurodevelopmental disorder characterized by disruptions in normal flow of speech in the form of repetition, prolongation and involuntary halts. Previously, mutations with more severe effects on GNPTAB and GNPTG have bee...
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Natural language processing of clinical notes for identification of critical limb ischemia.

International journal of medical informatics
BACKGROUND: Critical limb ischemia (CLI) is a complication of advanced peripheral artery disease (PAD) with diagnosis based on the presence of clinical signs and symptoms. However, automated identification of cases from electronic health records (EHR...

The distribution and redistribution of fentanyl & norfentanyl in post mortem samples.

Forensic science international
This article compares 249 post mortem case reports that were positive for fentanyl/norfentanyl. All the cases were submitted to, and analyzed by, the toxicology department of the Office of the Chief Medical Examiner, Edmonton, Alberta, Canada. This s...

Effect of bovine lactoferrin and human lactoferrin on the proliferative activity of the osteoblast cell line MC3T3-E1 in vitro.

Journal of dairy science
We conducted a comparative in vitro study on the proliferative effects of natural human lactoferrin (nhLF) and bovine lactoferrin (bLF) on osteoblasts. We investigated cell proliferation, cell survival, cell cycle, and mRNA and protein expression of ...
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Association of the CYP17 MSP AI (T-34C) and CYP19 codon 39 (Trp/Arg) polymorphisms with susceptibility to acne vulgaris.

Clinical and experimental dermatology
The aim of this study was to detect the association of the cytochrome P450 (CYP) 17 T-34C and CYP19 T

Novel real-time tumor-contouring method using deep learning to prevent mistracking in X-ray fluoroscopy.

Radiological physics and technology
Robustness to obstacles is the most important factor necessary to achieve accurate tumor tracking without fiducial markers. Some high-density structures, such as bone, are enhanced on X-ray fluoroscopic images, which cause tumor mistracking. Tumor tr...

Quantitative assessment of cancer cell morphology and motility using telecentric digital holographic microscopy and machine learning.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
The noninvasive, fast acquisition of quantitative phase maps using digital holographic microscopy (DHM) allows tracking of rapid cellular motility on transparent substrates. On two-dimensional surfaces in vitro, MDA-MB-231 cancer cells assume several...
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